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sivelestat

Known as: Glycine, N-(2-(((4-(2,2-dimethyl-1-oxopropoxy)phenyl)sulfonyl)amino)benzoyl)-, N-(2-(4-(2,2-dimethylpropionyloxy)phenylsulfonylamino)benzoyl)aminoacetic acid 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

GlycineSerine Proteinase InhibitorsSulfonamides

Narrower (1)

ONO 5046
Sivelestat Sodiumanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Neutrophil elastase inhibitor sivelestat ameliorates gefitinib, naphthalene-induced acute pneumonitis in mice
Neutrophil elastase inhibitor sivelestat ameliorates gefitinib, naphthalene-induced acute pneumonitis in mice. I ntroduction… 
2012
2012
The Effect of the Neutrophil Elastase Inhibitor Sivelestat on Early Injury after Liver Resection
BackgroundThe effects of sivelestat on endotoxin-induced lung injury, postperfusion lung injury, and ischemia–reperfusion are… 
2012
2012
Initial experience using Sivelestat to manage preterm labor with a bulging fetal membrane in pregnant women
Intrauterine infection and inflammation are recognized as major contributors to the onset of preterm labor. We describe two cases… 
2011
2011
Sivelestat Suppresses iNOS Gene Expression in Proinflammatory Cytokine-Stimulated Hepatocytes
BackgroundRecent evidence has indicated that sivelestat, a neutrophil elastase inhibitor, has liver-protective effects in a… 
2011
2011
Noninvasive In Vivo Quantification of Neutrophil Elastase Activity in Acute Experimental Mouse Lung Injury
We developed a neutrophil elastase-specific near-infrared fluorescence imaging agent, which, combined with fluorescence molecular… 
2010
2010
The impact of oxidative stress levels on the clinical effectiveness of sivelestat in treating acute lung injury: an electron spin resonance study.
BACKGROUND Sivelestat, a neutrophil elastase inhibitor, has been used to treat acute lung injury (ALI) with varying levels of… 
2006
2006
Clinical effects of a neutrophil elastase inhibitor, sivelestat, in patients with acute respiratory distress syndrome
PurposeWe assessed the effects of a neutrophil elastase inhibitor, sivelestat, on respiratory and organ functions as well as on… 
2006
2006
Sivelestat relieves respiratory distress refractory to dexamethasone in all-trans retinoic acid syndrome: a report of two cases
Abstract:  Treatment with all‐trans retinoic acid (ATRA) improves the prognosis of patients with acute promyelocytic leukemia… 
2005
2005
Protective effects of a selective neutrophil elastase inhibitor (sivelestat) on lipopolysaccharide-induced acute dysfunction of the pulmonary microcirculation
Objective:The purpose of this study was to evaluate the effect of a neutrophil elastase inhibitor, sivelestat, on… 
2005
2005
Epithelium-dependent and -independent inhibitory effects of sivelestat, a neutrophil elastase inhibitor, on substance P-induced contraction of airway smooth muscle in lipopolysaccharide-treated…
The underlying mechanism involved in the interaction between neutrophil elastase inhibitors and tachykinins has not been… 
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