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sivelestat

Known as: Glycine, N-(2-(((4-(2,2-dimethyl-1-oxopropoxy)phenyl)sulfonyl)amino)benzoyl)-, N-(2-(4-(2,2-dimethylpropionyloxy)phenylsulfonylamino)benzoyl)aminoacetic acid 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

GlycineSerine Proteinase InhibitorsSulfonamides

Narrower (1)

ONO 5046
Sivelestat Sodiumanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Neutrophil elastase inhibitor sivelestat ameliorates gefitinib, naphthalene-induced acute pneumonitis in mice
Neutrophil elastase inhibitor sivelestat ameliorates gefitinib, naphthalene-induced acute pneumonitis in mice. I ntroduction… 
2012
2012
The Effect of the Neutrophil Elastase Inhibitor Sivelestat on Early Injury after Liver Resection
BackgroundThe effects of sivelestat on endotoxin-induced lung injury, postperfusion lung injury, and ischemia–reperfusion are… 
2011
2011
Noninvasive In Vivo Quantification of Neutrophil Elastase Activity in Acute Experimental Mouse Lung Injury
We developed a neutrophil elastase-specific near-infrared fluorescence imaging agent, which, combined with fluorescence molecular… 
2011
2011
Sivelestat Suppresses iNOS Gene Expression in Proinflammatory Cytokine-Stimulated Hepatocytes
BackgroundRecent evidence has indicated that sivelestat, a neutrophil elastase inhibitor, has liver-protective effects in a… 
2010
2010
Neutrophil elastase contributes to the development of ischemia/reperfusion-induced liver injury by decreasing the production of insulin-like growth factor-I in rats.
2010
2010
The impact of oxidative stress levels on the clinical effectiveness of sivelestat in treating acute lung injury: an electron spin resonance study.
BACKGROUND Sivelestat, a neutrophil elastase inhibitor, has been used to treat acute lung injury (ALI) with varying levels of… 
2006
2006
Clinical effects of a neutrophil elastase inhibitor, sivelestat, in patients with acute respiratory distress syndrome
PurposeWe assessed the effects of a neutrophil elastase inhibitor, sivelestat, on respiratory and organ functions as well as on… 
2006
2006
Sivelestat relieves respiratory distress refractory to dexamethasone in all-trans retinoic acid syndrome: a report of two cases
Abstract:  Treatment with all‐trans retinoic acid (ATRA) improves the prognosis of patients with acute promyelocytic leukemia… 
2005
2005
Protective effects of a selective neutrophil elastase inhibitor (sivelestat) on lipopolysaccharide-induced acute dysfunction of the pulmonary microcirculation
Objective:The purpose of this study was to evaluate the effect of a neutrophil elastase inhibitor, sivelestat, on… 
2005
2005
Epithelium-dependent and -independent inhibitory effects of sivelestat, a neutrophil elastase inhibitor, on substance P-induced contraction of airway smooth muscle in lipopolysaccharide-treated…
The underlying mechanism involved in the interaction between neutrophil elastase inhibitors and tachykinins has not been… 
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