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site-specific telomere resolvase activity

Known as: ResT, TelN 
Catalysis of a site-specific breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Occurs via a… 
National Institutes of Health

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Broader (1)

Telomere Maintenance

Papers overview

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2017
2017
Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model
Vaccination with DNA that encodes cancer antigens is a simple and convenient way to raise immunity against cancer and has already… 
2012
2012
Construction and Characterization of an in-vivo Linear Covalently Closed DNA Vector Production System
BackgroundWhile safer than their viral counterparts, conventional non-viral gene delivery DNA vectors offer a limited safety… 
2008
2008
A rat model of saliva secretory immunoglobulin: a suppression caused by intense exercise
We aimed to develop a valid model of immunosuppression induced by intense exercise in rats. Rats were divided into three groups… 
Review
2006
Review
2006
Possibilities for reduction of nitrogen (N) excretion from ruminants and the need for further research - a review
Large proportions of consumed nitrogen are excreted via urine and feces. The excreted amounts vary in rumi­ nants between 60 and… 
Highly Cited
2005
Highly Cited
2005
Geometrie und Physik
  • H. Weyl
  • Naturwissenschaften
  • 2005
  • Corpus ID: 32457025
Die Votg~nge der Aul3enwelt spielen sich ab in Raura und Zeit, In der mathematischen Darstetlung erscheiner~ alle Zustandsgr6gen… 
2002
2002
Phage N15 Telomere Resolution
The Escherichia coli prophage N15 exists as a linear DNA molecule with covalently closed ends. Purified N15 protelomerase TelN is… 
2002
2002
Linear closed mini DNA generated by the prokaryotic cleaving-joining enzyme TelN is functional in mammalian cells
Abstract. For application of DNA in gene medicine plasmid or viral DNA is usually used as a vector for the gene of interest. To… 
Highly Cited
2000
Highly Cited
2000
The protelomerase of temperate Escherichia coli phage N15 has cleaving-joining activity.
Escherichia coli phage N15 encodes the slightly acidic, 630-residue protein of 72.2 kDa called protelomerase (TelN). TelN is a… 
Highly Cited
1995
Highly Cited
1995
In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues.
The development of camptothecin-like compounds as inhibitors of topoisomerase I for the treatment of resistant tumors has… 
1978
1978
CHLOROTETRACYCLINE AS AN INDICATOR OF THE INTERACTION OF CALCIUM WITH BRAIN MEMBRANE FRACTIONS
  • C. Carvalho
  • Journal of neurochemistry
  • 1978
  • Corpus ID: 9372765
Abstract— The fluorescence of chlorotetracycline (CTC) in the presence of synaptosomes isolated from sheep brain is selectively… 
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