simvastatin hydroxyacid
National Institutes of Health
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Verapamil is a calcium channel blocker commonly used in treatments of hypertension. Verapamil and its active metabolite…
BACKGROUND
Gender differences in pharmacokinetics have been reported to have important clinical consequences; however, no…
Osteogenic/osteoinductive systems combine simvastatin, poloxamine Tetronic 908 (T908) and α-cyclodextrins (αCDs) in a…
Preclinical information on the biliary metabolites of a drug candidate is typically obtained through the collection of bile after…
Since data concerning the toxicity and pharmacokinetics of concomitant repeated administration of grapefruit juice (GFJ) and…
Simvastatin hydroxy acid (1) is a well-known, potent HMG-CoA reductase inhibitor for the treatment of hypercholesterolemia. Its…
Simvastatin hydroxy acid (SVA), the pharmacologically active form of simvastatin (SV), is a potent inhibitor of 3-hydroxy-3…
All current 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors [simvastatin (SV), lovastatin (LV), atorvastatin, pravastatin…
A sensitive and specific method was developed and validated to quantitate lovastatin and its hydroxy acid in mouse and rat plasma…