A. Concheiro

Publications326
h-index50
Citations9,836
Highly Influential Citations169
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Light‐sensitive Intelligent Drug Delivery Systems †
Drug delivery systems (DDS) capable of releasing an active molecule at the appropriate site and at a rate that adjusts in response to the progression of the disease or to certain functions/biorhythms… Expand
  • 361
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Effect of batch variation and source of pulp on the properties of microcrystalline cellulose
Abstract We have investigated the characteristics of three batches of microcrystalline cellulose supplied by the same manufacturer but differing in the manufacturing process employed and/or the type… Expand
  • 76
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Imprinted soft contact lenses as norfloxacin delivery systems.
Soft contact lenses are receiving an increasing attention not only for correcting mild ametropia but also as drug delivery devices. To provide poly(hydroxyethyl methacrylate), PHEMA, lenses with the… Expand
  • 203
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Chemically cross-linked and grafted cyclodextrin hydrogels: from nanostructures to drug-eluting medical devices.
The unique ability of cyclodextrins (CDs) to form inclusion complexes can be transmitted to polymeric networks in which CDs are chemically grafted or cross-linked. Combination of CDs and hydrogels in… Expand
  • 115
  • 4
Incorporation of small quantities of surfactants as a way to improve the rheological and diffusional behavior of carbopol gels.
This paper analyzes the effects of Tween 80, Pluronic F-127, sodium dodecylsulfate (SDS), and benzalkonium chloride on the macro and microviscosity of Carbopol 934NF (0.25-0.50 g/dl) pharmaceutical… Expand
  • 86
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PEO-PPO-PEO Carriers for rAAV-Mediated Transduction of Human Articular Chondrocytes in Vitro and in a Human Osteochondral Defect Model.
Gene therapy is an attractive strategy for the durable treatment of human osteoarthritis (OA), a gradual, irreversible joint disease. Gene carriers based on the small human adeno-associated virus… Expand
  • 29
  • 4
Solubilization and stabilization of camptothecin in micellar solutions of pluronic-g-poly(acrylic acid) copolymers.
The capability of a family of copolymers comprising Pluronic (PEO-PPO-PEO) surfactants covalently conjugated with poly(acrylic acid) (Pluronic-PAA) to enhance the aqueous solubility and stability of… Expand
  • 107
  • 3
Smart drug delivery systems: from fundamentals to the clinic.
TLDR
We present a critical overview of therapeutically-interesting stimuli to trigger drug release and the evolution of responsive materials suitable as functional excipients. Expand
  • 203
  • 3
  • PDF
Temperature-sensitive chitosan-poly(N-isopropylacrylamide) interpenetrated networks with enhanced loading capacity and controlled release properties.
Interpenetrated polymer networks (IPN) of poly(N-isopropylacrylamide) (PNIPA) and chitosan (two grades) were prepared by free radical polymerisation and cross-linking of PNIPA (700 mM) with… Expand
  • 149
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Self-associative behavior and drug-solubilizing ability of poloxamine (tetronic) block copolymers.
The incidence of the structural features on the self-assembly of different poloxamines (the conventional sequential Tetronic 304, 901, 904, 908, 1107, 1301, and 1307; a reverse-sequential counterpart… Expand
  • 94
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