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- Publications
- Influence
Light‐sensitive Intelligent Drug Delivery Systems †
- C. Alvarez-Lorenzo, L. Bromberg, A. Concheiro
- Chemistry, Medicine
- Photochemistry and photobiology
- 1 July 2009
Drug delivery systems (DDS) capable of releasing an active molecule at the appropriate site and at a rate that adjusts in response to the progression of the disease or to certain functions/biorhythms… Expand
Effect of batch variation and source of pulp on the properties of microcrystalline cellulose
- M. Landín, R. Martínez-Pacheco, J. L. Gómez-Amoza, C. Souto, A. Concheiro, R. Rowe
- Materials Science
- 26 April 1993
Abstract We have investigated the characteristics of three batches of microcrystalline cellulose supplied by the same manufacturer but differing in the manufacturing process employed and/or the type… Expand
Imprinted soft contact lenses as norfloxacin delivery systems.
- C. Alvarez-Lorenzo, Fernando Yáñez, R. Barreiro-Iglesias, A. Concheiro
- Chemistry, Medicine
- Journal of controlled release : official journal…
- 20 July 2006
Soft contact lenses are receiving an increasing attention not only for correcting mild ametropia but also as drug delivery devices. To provide poly(hydroxyethyl methacrylate), PHEMA, lenses with the… Expand
Chemically cross-linked and grafted cyclodextrin hydrogels: from nanostructures to drug-eluting medical devices.
- A. Concheiro, C. Alvarez-Lorenzo
- Chemistry, Medicine
- Advanced drug delivery reviews
- 1 August 2013
The unique ability of cyclodextrins (CDs) to form inclusion complexes can be transmitted to polymeric networks in which CDs are chemically grafted or cross-linked. Combination of CDs and hydrogels in… Expand
Incorporation of small quantities of surfactants as a way to improve the rheological and diffusional behavior of carbopol gels.
- R. Barreiro-Iglesias, C. Alvarez-Lorenzo, A. Concheiro
- Chemistry, Medicine
- Journal of controlled release : official journal…
- 9 November 2001
This paper analyzes the effects of Tween 80, Pluronic F-127, sodium dodecylsulfate (SDS), and benzalkonium chloride on the macro and microviscosity of Carbopol 934NF (0.25-0.50 g/dl) pharmaceutical… Expand
PEO-PPO-PEO Carriers for rAAV-Mediated Transduction of Human Articular Chondrocytes in Vitro and in a Human Osteochondral Defect Model.
- A. Rey-Rico, Janina Frisch, +7 authors M. Cucchiarini
- Materials Science, Medicine
- ACS applied materials & interfaces
- 3 August 2016
Gene therapy is an attractive strategy for the durable treatment of human osteoarthritis (OA), a gradual, irreversible joint disease. Gene carriers based on the small human adeno-associated virus… Expand
Solubilization and stabilization of camptothecin in micellar solutions of pluronic-g-poly(acrylic acid) copolymers.
- R. Barreiro-Iglesias, L. Bromberg, Marina Temchenko, T. A. Hatton, A. Concheiro, C. Alvarez-Lorenzo
- Chemistry, Medicine
- Journal of controlled release : official journal…
- 7 July 2004
The capability of a family of copolymers comprising Pluronic (PEO-PPO-PEO) surfactants covalently conjugated with poly(acrylic acid) (Pluronic-PAA) to enhance the aqueous solubility and stability of… Expand
Smart drug delivery systems: from fundamentals to the clinic.
- C. Alvarez-Lorenzo, A. Concheiro
- Computer Science, Medicine
- Chemical communications
- 24 June 2014
TLDR
Temperature-sensitive chitosan-poly(N-isopropylacrylamide) interpenetrated networks with enhanced loading capacity and controlled release properties.
- C. Alvarez-Lorenzo, A. Concheiro, A. Dubovik, N. V. Grinberg, T. Burova, V. Grinberg
- Chemistry, Medicine
- Journal of controlled release : official journal…
- 16 February 2005
Interpenetrated polymer networks (IPN) of poly(N-isopropylacrylamide) (PNIPA) and chitosan (two grades) were prepared by free radical polymerisation and cross-linking of PNIPA (700 mM) with… Expand
Self-associative behavior and drug-solubilizing ability of poloxamine (tetronic) block copolymers.
- J. Gonzalez-Lopez, C. Alvarez-Lorenzo, Pablo Taboada, A. Sosnik, I. Sández-Macho, A. Concheiro
- Chemistry, Medicine
- Langmuir : the ACS journal of surfaces and…
- 12 September 2008
The incidence of the structural features on the self-assembly of different poloxamines (the conventional sequential Tetronic 304, 901, 904, 908, 1107, 1301, and 1307; a reverse-sequential counterpart… Expand