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sesquiterpene synthase activity

Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene… 
National Institutes of Health

Papers overview

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2017
2017
β-Eudesmol, an oxygenized sesquiterpene, stimulates appetite via TRPA1 and the autonomic nervous system
Transient receptor potential ankyrin 1 (TRPA1) is a calcium-permeable non-selective cation channel, which is activated by various… 
2012
2012
Dactylomelatriol, a biogenetically intriguing omphalane-derived marine sesquiterpene.
Dactylomelatriol (1), obtained from the sea hare Aplysia dactylomela, is the first naturally occurring omphalane-derived… 
2009
2009
A concise total synthesis of (+/-)-anthecularin.
A total synthesis of the novel sesquiterpene anthecularin 1, isolated from Greek Anthemis auriculata, based on an intramolecular… 
2006
2006
Engineering cotton (+)-delta-cadinene synthase to an altered function: germacrene D-4-ol synthase.
The combined approaches of rational design and random mutagenesis were applied to generate a sesquiterpene synthase with an… 
2006
2006
Trichodiene Synthase: Synthesis and Inhibition Kinetics of 12‐Fluoro‐farnesylphosphonophosphate for Sesquiterpene Cyclases
trans, trans-Farnesyl diphosphate (FPP) serves as a universal substrate for a large family of sesquiterpene cyclases that are… 
2003
2003
Studies on Quinones. Part 38: synthesis and leishmanicidal activity of sesquiterpene 1,4-Quinones.
2003
2003
Synthetic studies towards pteridanone, a novel protoilludane-type tricyclic sesquiterpenoid
A synthetic approach directed towards the total synthesis of the novel protoilludane sesquiterpene pteridanone, the aglycon of… 
Highly Cited
2002
Highly Cited
2002
Biosynthesis of the sesquiterpene germacrene D in Solidago canadensis: 13C and (2)H labeling studies.
Highly Cited
2001
Highly Cited
2001
Comparison of volatile compounds isolated from the skin and flesh of four potato cultivars after baking.
Four potato cultivars, Cara, Nadine, Fianna, and Marfona, were selected. Potatoes were baked in their skins prior to separating… 
Highly Cited
2000
Highly Cited
2000
Molecular cloning, expression, and characterization of amorpha-4,11-diene synthase, a key enzyme of artemisinin biosynthesis in Artemisia annua L.
In plants, sesquiterpenes of different structural types are biosynthesized from the isoprenoid intermediate farnesyl diphosphate… 
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