• Publications
  • Influence
The chemistry of marine pulmonate gastropods.
Secondary metabolites from pulmonate molluscs of the genera Siphonaria, Onchidium, and Trimusculus are described and strong resemblance between class I and cephalaspidean metabolites and between class II and onchidiid metabolites encourages speculation about their biosynthetic and phylogenetic relationship. Expand
Carijodienone from the octocoral Carijoa multiflora. A spiropregnane-based steroid.
Two new steroids (1 and 2) and the known pregna-1,4,20-trien-3-one (3) have been isolated from the Pacific octocoral Carijoa multiflora. Compound 1 possesses a novel spiropregnane-based steroidalExpand
Unusual chlorinated pregnanes from the eastern Pacific octocoral Carijoa multiflora
Abstract Two unique chloro-pregnane steroids have been isolated from the eastern Pacific octocoral Carijoa multiflora and their structures and stereochemistries were determined on the basis ofExpand
Aplysiadiol from Aplysia dactylomela suggested a key intermediate for a unified biogenesis of regular and irregular marine algal bisabolene-type metabolites
The rearranged compound 1, the regular 2 and 3 and the degraded 4 are novel bisabolene-type metabolites that along with the known compounds caespitol, 8-acetylcaespitol, caespitane, caespitenone,Expand
Dactylomelatriol, a biogenetically intriguing omphalane-derived marine sesquiterpene.
Dactylomelatriol (1), obtained from the sea hare Aplysia dactylomela, is the first naturally occurring omphalane-derived sesquiterpene from the marine environment. From this species the knownExpand
In a screening of Basidiomycete cultures isolated from marine invertebrates collected along the Chilean coastline, a Penicillium brevicompactum strain was identified as a producer of metabolites inhibiting the growth of bacteria and fungi. Expand
Neopetrosiamides, peptides from the marine sponge Neopetrosia sp. that inhibit amoeboid invasion by human tumor cells.
Two diastereomeric tricyclic peptides that inhibit amoeboid invasion of human tumor cells, have been isolated from the marine sponge Neopetrosia sp. Expand
3-Keto-22-epi-28-nor-cathasterone, a brassinosteroid-related metabolite from Cystoseira myrica
Bioassay-guided purification of an ethanolic extract of Cystoseira myrica against HEPG-2 and HCT116 human cancer cell lines led to the isolation of 3-keto-22-epi-28-nor-cathasterone, 1 and cholest-4-ene-3,6-dione, 2, allowing for the first time that a brassinosteroid-related metabolite occurs in seaweed. Expand
Novel lactone chamigrene-derived metabolites from Laurencia majuscula
Gomerolactones A–D along with the known majusculone, obtusol, and elatol were isolated from Laurencia majuscula, and their structures were determined spectroscopically. With the aid of Pirkle'sExpand
Pronuciferine N-oxide, a proaporphine N-oxide alkaloid from Berberis coletioides.
Compound 1 is the first naturally occurring proaporphine N-methyl-N-oxide alkaloid with an N-oxide functionality, and was determined by spectroscopic evidence. Expand