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Antileishmanial and trypanocidal activity of Brazilian Cerrado plants.
TLDR
Thirty one extracts of thirteen medicinal plants from the Brazilian Cerrado were evaluated in vitro for their antiprotozoal activity against promastigotes of Leishmania donovani, and amastigote of Trypanosoma cruzi, and among the selected plants, Casearia sylvestris var.
Activity of compounds isolated from Chilean lichens against experimental cutaneous leishmaniasis.
2-substituted quinoline alkaloids as potential antileishmanial drugs
TLDR
This study is the first to show the activity of 2-substituted quinoline alkaloids for experimental treatment of New World cutaneous leishmaniasis and further investigations of these compounds might yet prove helpful for the development of new antileishmanial drugs.
Comparative evaluation of pyrethroid insecticide formulations against Triatoma infestans (Klug): residual efficacy on four substrates.
TLDR
WP formulations were not as effective as SC flowable formulations but, overall in the longer term, WP gave grater mortality rates of T. infestans nymphs exposed at up to six months post-spraying.
Antiprotozoal activity of Jatrogrossidione from Jatropha grossidentata and Jatrophone from Jatropha isabellii
TLDR
Jatrogrossidione showed a strong in vitro leishmanicidal and trypanocidal activity with IC100 of 0.75 and 1.0 μg/mL, respectively, against Leishmania and Trypanosoma cruzi strains in vitro as well as againstLeishmania amazonensis in vivo.
Effect of natural naphthoquinones in BALB/c mice infected with Leishmania amazonensis and L. venezuelensis.
TLDR
Assays of a single local treatment on foot-pad infection two weeks after the parasitic inoculation with L. amazonensis showed that 8,8'-biplumbagin (50 mg/kg/d) was as potent as Glucantime (400 mg/ kg/d).
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