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Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases
TLDR
Cbp is revealed as a new component of the regulatory mechanism controlling the activity of membrane-associated Src-PTKs, involved in the membrane localization of Csk and in the Csk-mediated inhibition of c-Src. Expand
Parasympathetic and sympathetic control of the pancreas: A role for the suprachiasmatic nucleus and other hypothalamic centers that are involved in the regulation of food intake
TLDR
The appearance of third‐order neurons located in the sympathetic SPN after complete sympathectomy and in the DMV after complete vagotomy illustrates the possibility that motor neurons of the sympathetic and parasympathetic system may exchange information by means of interneurons. Expand
The suprachiasmatic nucleus balances sympathetic and parasympathetic output to peripheral organs through separate preautonomic neurons
TLDR
There are two separate populations of pre‐sympathetic and pre‐parasympathetic neurons within the paraventricular nucleus of the hypothalamus, Interestingly, this segregation persists into the SCN, where, as a result, the day‐night balance in autonomic function of the organs is affected by specialized pre‐Sympathetic or pre‐ parasympathy SCN neurons. Expand
Suprachiasmatic Nucleus Circadian Oscillatory Protein, a Novel Binding Partner of K-Ras in the Membrane Rafts, Negatively Regulates MAPK Pathway*
TLDR
A substantial amount of SCOP was localized in the brain membrane rafts, in which only K-Ras was abundant among Ras isoforms, identifying a novel mechanism for regulation of the Ras-MAPK pathway. Expand
Effects of intraduodenal injection of Lactobacillus johnsonii La1 on renal sympathetic nerve activity and blood pressure in urethane-anesthetized rats
TLDR
The findings suggest that LJLa1 or its metabolites might lower BP by changing autonomic neurotransmission via the central histaminergic nerves and the suprachiasmatic nucleus in rats. Expand
Changes in light-induced phase shift of circadian rhythm in mice lacking PACAP.
TLDR
The phase advance in PACAP(-/-) mice by a light stimulation at late subjective night was significantly attenuated, but the phase delay due to the illumination at the early subjective night slightly diminished, which provides new aspects about the roles of PACAP in light-induced phase shift of the circadian clock. Expand
Light and Glutamate-Induced Degradation of the Circadian Oscillating Protein BMAL1 during the Mammalian Clock Resetting
TLDR
Robust circadian BMAL1-IR oscillations with nocturnal peaks were detected in the rat suprachiasmatic nuclei (SCN) during a light/dark cycle and under constant darkness, and a rapid decrease of BMal1 protein suggests that BMAL2 protein might be implicated in the light-transducing pathway within the SCN. Expand
CKIε/δ-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock
TLDR
The degradation rate of PER2, which is regulated by CKIε/δ-dependent phosphorylation, was temperature-insensitive in living clock cells, yet sensitive to chemical perturbations, revealing its high sensitivity tochemical perturbation. Expand
Identification of tudor repeat associator with PCTAIRE 2 (Trap). A novel protein that interacts with the N-terminal domain of PCTAIRE 2 in rat brain.
TLDR
Immunohistochemical analyses showed that PCTAIRE 2 and Trap were distributed in the same cell layer of the cerebral cortex and cerebellum, and suggest that Trap is a physiological partner of PCT AIRE 2 in terminally differentiated neurons. Expand
Possible Role of L-Carnosine in the Regulation of Blood Glucose through Controlling Autonomic Nerves
TLDR
It is suggested that L-carnosine released from muscles due to exercise functions to reduce the blood glucose level through the regulation of the autonomic nerves via H3 receptor. Expand
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