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seratrodast

Known as: 7-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoic acid, Benzeneheptanoic acid, zeta-(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-, (+-)- 
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (2)

AA 2414ABT-001

Broader (5)

Anti-Asthmatic AgentsAnti-Inflammatory Agents, Non-SteroidalBenzoquinonesHeptanoic Acids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Indium-catalyzed synthesis of keto esters from cyclic 1,3-diketones and alcohols and application to the synthesis of seratrodast.
Esterification reactions from cyclic 1,3-diketones and alcohols are carried out in the presence of several Lewis acids. In… 
2008
2008
Effects of KP‐496, a novel dual antagonist at the cysteinyl leukotriene receptor 1 and the thromboxane A2 receptor, on airway obstruction in guinea pigs
KP‐496 is a novel dual antagonist for cysteinyl leukotriene receptor 1 (CysLT1) and thromboxane A2 (TXA2) receptor (TP). The aim… 
2007
2007
Participation in cysteinyl leukotrienes and thromboxane A2 in nasal congestion model in Brown Norway rats.
2004
2004
Synergism between cysteinyl leukotrienes and thromboxane A2 to induce allergic late phase nasal blockage in guinea pigs.
2003
2003
The Effect of Seratrodast on Eosinophil Cationic Protein and Symptoms in Asthmatics
Thromboxane A2 (TXA2), an arachidonate derivative, is a potent bronchoconstrictor; therefore, blocking TXA2 should attenuate… 
2002
2002
Study on the Usefulness of Seratrodast in the Treatment of Chronic Pulmonary Emphysema
Summary It has been reported that the biosynthesis of thromboxane A2 (TXA2) is enhanced in platelets in the presence of chronic… 
2001
2001
Involvement of thromboxane A2 and peptide leukotrienes in early and late phase nasal blockage in a guinea pig model of allergic rhinitis
Abstract. Objective and design: We investigated the effects of the thromboxane (TX) A2 antagonist seratrodast, the peptide… 
2001
2001
Pharmacological characterization of the leukocyte kinetics after intranasal antigen challenge in a guinea pig model of allergic rhinitis
Abstract. Objective and design: We characterized the leukocyte kinetics after antigen challenge, and investigated the effects of… 
2000
2000
Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs.
1996
1996
Chapter 34. To Market, To Market - 1995
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