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seratrodast

Known as: 7-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoic acid, Benzeneheptanoic acid, zeta-(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-, (+-)- 
 
National Institutes of Health

Papers overview

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2015
2015
Remote hind limb preconditioning (RIPC) is a protective strategy in which short episodes of ischemia and reperfusion in a remote… Expand
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2003
2003
Thromboxane A2 (TXA2), an arachidonate derivative, is a potent bronchoconstrictor; therefore, blocking TXA2 should attenuate… Expand
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2002
2002
It has been reported that the biosynthesis of thromboxane A2 (TXA2) is enhanced in platelets in the presence of chronic… Expand
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2002
2002
A novel method for thermodynamic stability studies of polymorphic drug substances has been developed. In order to estimate the… Expand
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2001
2001
Abstract. Objective and design: We investigated the effects of the thromboxane (TX) A2 antagonist seratrodast, the peptide… Expand
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1999
1999
The crystal structure of seratrodast (AA-2414), a potent thromboxane A2 (TXA2) receptor antagonist, served as starting point to… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND AND PURPOSE The effects of acute smoking on cerebral circulation are controversial. This study was designed (1) to… Expand
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1997
1997
BACKGROUND Seratrodast, a potent thromboxane receptor antagonist, is approved in Japan for the treatment of asthma and currently… Expand
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1997
1997
Seratrodast (ABT-001, AA-2414) undergoes cytochrome P450 (CYP)-dependent metabolism to a major (5-methylhydroxy seratrodast; 5… Expand
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1997
1997
To identify the chemical mediators involved in the pathogenesis of allergic rhinitis, we studied the effects of the thromboxane… Expand
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