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AA 2414

Known as: AA-2414 
National Institutes of Health

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seratrodast

Papers overview

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2007
2007
Leukotrienes and cyclooxygenase products mediate anaphylactic venoconstriction in ovalbumin sensitized rat livers.
2004
2004
Human bronchial smooth muscle cell proliferation via thromboxane A2 receptor.
1996
1996
Characterization of thromboxane A2/prostaglandin endoperoxide receptors in aorta.
1994
1994
Antagonism of the human thromboxane A2 receptor by an anti-asthmatic agent AA-2414.
The human thromboxane A2 receptor (TXA2-R)-coding gene was introduced into Chinese hamster ovary cells and a cell line (TCHO-25… 
Highly Cited
1994
Highly Cited
1994
Pharmacological modulation of immediate and late airway response and leukocyte infiltration in the guinea pig.
We established an experimental model of late asthmatic response (LAR) using conscious guinea pigs actively sensitized by antigen… 
Highly Cited
1991
Highly Cited
1991
Effect of a thromboxane A2 receptor antagonist (AA-2414) on bronchial hyperresponsiveness to methacholine in subjects with asthma.
1990
1990
The role of thromboxane (TX) A2 in rabbit arterial thrombosis induced by endothelial damage.
1990
1990
Antagonistic action of AA-2414 on thromboxane A2/prostaglandin endoperoxide receptor in platelets and blood vessels.
AA-2414, (+/-)-7-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoi c acid, inhibited the aggregation of guinea pig… 
1989
1989
Endothelin-induced mobilization of Ca2+ and the possible involvement of platelet activating factor and thromboxane A2.
Highly Cited
1989
Highly Cited
1989
A novel anti-asthmatic quinone derivative, AA-2414 with a potent antagonistic activity against a variety of spasmogenic prostanoids.
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