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securinine

Known as: (6S,11aR,11bS)-9,10,11,11a-Tetrahydro-8H-6,11b-methanofuro(2,3-c)pyrido(1,2-a)azepin-2(6H)-one, securinan-11-one 
National Institutes of Health

Related topics

Related topics

8 relations

Broader (4)

AzepinesHeterocyclic Compounds, Bridged-RingLactonesPiperidines

Narrower (4)

allonorsecurinineallosecurininesecurinine methiodidesecurinine nitrate

Papers overview

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1999
1999
Securinine induced apoptosis in K562 cells
AIM To study whether securinine (SEC) could induce apoptosis in K562 cells.METHODS Cell inhibitory effect was assessed by MTT… 
1988
1988
The formal total synthesis of securinine
Securinine (Ⅰ) was synthesized using α-ketol (Ⅱ) as the starting material by acetylation, bromination, elimination and… 
1987
1987
Influence of securinine on 5 kinds of neurotransmitter receptors and membrane potential of the frog spinal cord
Using radioligand binding assay method, securinine was shown to be specifically bound to GABA receptors of rat brain with IC_(50… 
1967
1967
[Pharmacodynamics of securinine, present in Phyllanthus discoïdes-Euphorbiaceae].
1966
1966
Total synthesis of securinine.
1965
1965
Synthesis and stereochemistry in B/C ring juncture of lactam-carbinol A, a degradation product of securinine.
Cis-and trans-2-Hydroxy-2-(2-pyridyl) cyclohexaneacetic acid, (X) and (VIII), were synthesized and their stereochemistries… 
1963
1963
ON THE ABSOLUTE CONFIGURATION OF SECURININE.
1963
1963
THE STRUCTURE OF SECURININE
This paper reports the structural elucidation of securinine, a lactonic alkaloid of composition C_(13)H_(15)O_2N (VII; for… 
1958
1958
Result of application of securinine in acute poliomyelitis
1956
1956
[Pharmacology of a new alkaloid securinine].
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