securinine

Known as: (6S,11aR,11bS)-9,10,11,11a-Tetrahydro-8H-6,11b-methanofuro(2,3-c)pyrido(1,2-a)azepin-2(6H)-one, securinan-11-one 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1956-2017
0519562016

Papers overview

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2011
2011
As the defining feature of Acute Myeloid Leukemia (AML) is a maturation arrest, a highly desirable therapeutic strategy is to… (More)
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Highly Cited
2010
Highly Cited
2010
Metastasis is the major cause of cancer mortality. We aimed to find a metastasis-prone signature for early stage mismatch-repair… (More)
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2010
2010
The identification of agents that preferentially kill cancer cells while protecting normal cells offers the potential to overcome… (More)
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2007
2007
Innate immune cell stimulation represents a complementary approach to vaccines and antimicrobial drugs to counter infectious… (More)
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2005
2005
Crude extracts and active principles from medicinal plants have shown potential role in controlling plant diseases in glasshouses… (More)
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2004
2004
The effects of (+) securinine on behavior and morphological changes after intracerebral ventricle injection of beta-amyloid (25… (More)
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2001
2001
Pharmacological activities of virosecurinine (Vse) and securinine (Sec) were studied. The results showed that acute toxicity of… (More)
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1999
1999
AIM To study whether securinine might induce apoptosis in human leukemia HL-60 cells. METHODS Inhibition of proliferation was… (More)
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1985
1985
Experiments were undertaken to determine the site of action of securinine and related convulsant indolizidines. All of these… (More)
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1984
1984
From the aerial parts of PHYLLANTHUS NIRURI L. (Euphorbiaceae) plant two alkaloids 4-methoxy-securinine (phyllanthine) ( 1) and 4… (More)
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