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sceptrin

 
National Institutes of Health

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Pyrroles

Papers overview

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Highly Cited
2014
Highly Cited
2014
Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence
Cycloaddition is an essential tool in chemical synthesis. Instead of using light or heat as a driving force, marine sponges… Expand
2010
2010
Sceptrin, a Marine Natural Compound, Inhibits Cell Motility in a Variety of Cancer Cell Lines
Sceptrin, a natural compound produced by various marine sponges, was tested for its effect on cell motility. We report for the… Expand
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2008
2008
Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol.
A bidirectional affinity system was used to screen for marine natural products that bound to Escherichia coli proteins. A system… Expand
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Highly Cited
2008
Highly Cited
2008
Synthesis of cyclobutenes by highly selective transition-metal-catalyzed ring expansion of cyclopropanes.
The four-membered ring is an important structural motif, present in many bioactive natural products and key intermediates in the… Expand
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2007
2007
Total synthesis of dimeric pyrrole-imidazole alkaloids: sceptrin, ageliferin, nagelamide e, oxysceptrin, nakamuric acid, and the axinellamine carbon skeleton.
The dimeric pyrrole imidazole natural products are a growing class of alkaloids with exotic connectivity, unique topologies, high… Expand
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Highly Cited
2006
Highly Cited
2006
Cyclic heptapeptides from the Jamaican sponge Stylissa caribica.
Two new cyclic heptapeptides, stylisin 1(1) and stylisin 2 (2), were isolated and characterized from the Jamaican sponge Stylissa… Expand
Highly Cited
2004
Highly Cited
2004
Short total synthesis of (+/-)-sceptrin.
Gifted with novel chemical features and extraordinary biological activity, sceptrin has remained a prominent unanswered synthetic… Expand
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2004
2004
Brominated pyrrole alkaloids from marine Agelas sponges reduce depolarization-induced cellular calcium elevation.
Seven pyrrole alkaloids isolated from Agelas sponges were tested for interactions with the cellular calcium homeostasis… Expand
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Highly Cited
2000
Highly Cited
2000
Chemical defenses of the Caribbean sponges Agelas wiedenmayeri and Agelas conifera
Previous studies have determined that Caribbean reef sponges of the genus Agelas are chemically defended from fish predation by… Expand
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1993
1993
A study on the mechanism of action of sceptrin, an antimicrobial agent isolated from the South Pacific sponge Agelas mauritiana.
The mechanism of action of sceptrin, an antimicrobial agent isolated from the sponge Agelas mauritiana, was investigated… Expand
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