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Oxepinamides A-C and fumiquinazolines H--I: bioactive metabolites from a marine isolate of a fungus of the genus Acremonium.
Three new oxepin-containing natural products (1-3) and two new fumiquinazoline metabolites (4-5) have been isolated from organic extracts of the culture broth and mycelia of an Acremonium sp., a… Expand
Brominated pyrrole alkaloids from marine Agelas sponges reduce depolarization-induced cellular calcium elevation.
- U. Bickmeyer, C. Drechsler, M. Köck, M. Assmann
- Medicine, Biology
- Toxicon : official journal of the International…
- 1 July 2004
Seven pyrrole alkaloids isolated from Agelas sponges were tested for interactions with the cellular calcium homeostasis. Brominated pyrrole alkaloids reduced voltage dependent calcium elevation in… Expand
Chemical defenses of the Caribbean sponges Agelas wiedenmayeri and Agelas conifera
Previous studies have determined that Caribbean reef sponges of the genus Agelas are chemically defended from fish predation by brominated pyrrole alkaloids, and that the compounds responsible for… Expand
Secretory acid ribonucleases from tomato, Lycopersicon esculentum Mill.
2D‐NMR‐Guided Constitutional Analysis of Organic Compounds Employing the Computer Program COCON[#]
Synthesis of the marine natural product nalpha-(4-bromopyrrolyl-2-carbonyl)-L-homoarginine, a putative biogenetic precursor of the pyrrole-imidazole alkaloids.
- T. Lindel, M. Hochgürtel, M. Assmann, M. Köck
- Chemistry, Medicine
- Journal of natural products
- 23 September 2000
Lysine is proposed as an alternative biosynthetic precursor of the pyrrole-imidazole alkaloids frequently found in marine sponges. As a putative key intermediate, the natural product… Expand
Bioactive metabolites from the Caribbean sponge Aka coralliphagum.
- A. Grube, M. Assmann, E. Lichte, F. Sasse, J. Pawlik, M. Köck
- Medicine, Chemistry
- Journal of natural products
- 20 February 2007
The chemistry of the burrowing sponge Aka coralliphagum was investigated to identify chemically labile secondary metabolites. The HPLC-MS analysis of the two growth forms typica and incrustans… Expand
Linear diterpenes from the marine brown alga Bifurcaria bifurcata: a chemical perspective
This article will give a complete overview of linear diterpenes isolated from the brown alga Bifurcaria bifurcata. For this purpose all published acyclic diterpenoids are listed and gathered in three… Expand
Further eleganolone-derived diterpenes from the brown alga Bifurcaria bifurcata
Abstract Four new diterpenes ( 1 – 4 ) together with six known members of this family were isolated from the brown alga Bifurcaria bifurcata collected off the coast near Roscoff, France. The… Expand
Reinvestigation of the Conformation of Cyclosporin A in Chloroform
New investigations of cyclosporin A in CDCl3 have been performed to obtain additional and more accurate distance restraints than utilized in our previous studies of cyclosporin A. Build-up rates at… Expand