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saporin

Known as: RIP protein, Saponaria officinalis, ribosome-inactivating protein, S. officinalis, saporin protein, Saponaria officinalis 
National Institutes of Health

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4 relations

Broader (4)

Antineoplastic Agents, PhytogenicImmunotoxinsProtein Synthesis Inhibitorssaporins

Papers overview

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2011
2011
Control of the central chemoreflex by A5 noradrenergic neurons in rats
2007
2007
Estradiol enhances DMP acquisition via a mechanism not mediated by turning strategy but which requires intact basal forebrain cholinergic projections
Highly Cited
2005
Highly Cited
2005
Basomedial hypothalamic injections of neuropeptide Y conjugated to saporin selectively disrupt hypothalamic controls of food intake.
Neuropeptide Y (NPY) conjugated to saporin (NPY-SAP), a ribosomal inactivating toxin, is a newly developed compound designed to… 
2003
2003
Ribosome‐inactivating proteins depurinate poly(ADP‐ribosyl)ated poly(ADP‐ribose) polymerase and have transforming activity for 3T3 fibroblasts
Highly Cited
2001
Highly Cited
2001
The effects of manipulations of attentional demand on cortical acetylcholine release.
Highly Cited
2000
Highly Cited
2000
Cortical cholinergic inputs mediate processing capacity: effects of 192 IgG‐saporin‐induced lesions on olfactory span performance
An olfactory span task that required rats to discriminate an olfactory stimulus added to an increasing list of such stimuli… 
Highly Cited
1997
Highly Cited
1997
Effects of cholinergic denervation on seizure development and neurotrophin messenger RNA regulation in rapid hippocampal kindling
Highly Cited
1996
Highly Cited
1996
Polynucleotide: adenosine glycosidase activity of saporin-L1: effect on DNA, RNA and poly(A).
The ribosome-inactivating proteins (RIPs) are a family of plant enzymes for which a unique activity has been determined: rRNA N… 
Highly Cited
1992
Highly Cited
1992
Ber‐H2 (anti‐CD30)‐saporin immunotoxin: a new tool for the the treatment of Hodgkin's disease and CD30+ lymphoma: in vitro evaluation
An immunotoxin containing an anti‐CD30 monoclonal antibody (Ber‐H2) and saporin, a ribosome‐inactivating protein type 1, is… 
Highly Cited
1988
Highly Cited
1988
Bispecific F(ab' gamma)2 antibody for the delivery of saporin in the treatment of lymphoma.
This work describes the successful use of bispecific F(ab' gamma)2 antibody (Ab) in combination with a ribosome-inactivating… 
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