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Locus coeruleus noradrenergic neurons and CO2 drive to breathing
The Locus coeruleus (LC) has been suggested as a CO2 chemoreceptor site in mammals. In the present study, we assessed the role of LC noradrenergic neurons in the cardiorespiratory and thermalExpand
Locus coeruleus is a central chemoreceptive site in toads.
The locus coeruleus (LC) has been suggested as a CO2 chemoreceptor site in mammals. This nucleus is a mesencephalic structure of the amphibian brain and is probably homologous to the LC in mammals.Expand
Control of breathing in anuran amphibians.
The primary role of the respiratory system is to ensure adequate tissue oxygenation, eliminate carbon dioxide and help to regulate acid-base status. To maintain this homeostasis, amphibians possessExpand
The locus coeruleus and central chemosensitivity
The locus coeruleus (LC) lies in the dorsal pons and supplies noradrenergic (NA) input to many regions of the brain, including respiratory control areas. The LC may provide tonic input for basalExpand
Seasonal changes in the preferred body temperature, cardiovascular, and respiratory responses to hypoxia in the toad, Bufo paracnemis.
Estivation is accompanied by a reduction of oxygen consumption in amphibians during drought. We tested the hypothesis that, during the dry season, the toad Bufo paracnemis selects a lower preferredExpand
Raphe magnus nucleus is involved in ventilatory but not hypothermic response to CO2.
There is evidence that serotonin [5-hydroxytryptamine (5-HT)] is involved in the physiological responses to hypercapnia. Serotonergic neurons represent the major cell type (comprising 15-20% of theExpand
TRPV4 activates autonomic and behavioural warmth‐defence responses in Wistar rats
In this study, we aimed at investigating the involvement of the warmth‐sensitive channel – TRPV4 (in vitro sensitive to temperatures in the range of approx. 24–34 °C) – on the thermoregulatoryExpand
Nitric oxide pathway in the nucleus raphe magnus modulates hypoxic ventilatory response but not anapyrexia in rats
Nucleus raphe magnus (NRM) is one of the cellular groups of the brainstem that is involved in the physiologic responses to hypoxia and contains nitric oxide (NO) synthase. In the present study, weExpand
Serotonergic neurons in the nucleus raphe obscurus contribute to interaction between central and peripheral ventilatory responses to hypercapnia
Serotonergic (5-HT) neurons in the nucleus raphe obscurus (ROb) are involved in the respiratory control network. However, it is not known whether ROb 5-HT neurons play a role in the functionalExpand
Role of Locus coeruleus noradrenergic neurons in cardiorespiratory and thermal control during hypoxia
We investigated the specific role of LC noradrenergic (NA) neurons in the cardiorespiratory and thermal responses to hypoxia. Aiming this, LC NA neurons were selectively destroyed by microinjectingExpand
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