salubrinal

 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The mechanisms leading to neuronal death in neurodegenerative disease are poorly understood. Many of these disorders, including… (More)
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2011
2011
Cadmium exposure is known to cause endoplasmic reticulum (ER) stress. In our current study, we examined the effects of salubrinal… (More)
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2011
2011
Although cisplatin attacks various tumors with remarkable efficacy, its clinical usage has been limited by its side effects… (More)
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Highly Cited
2009
Highly Cited
2009
The mechanisms underlying disease manifestations in neurodegeneration remain unclear, but their understanding is critical to… (More)
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Highly Cited
2009
Highly Cited
2009
The endoplasmic reticulum(ER) stress plays a vital role in mediating ischemic neuronal cell death. However, very little is known… (More)
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Highly Cited
2008
Highly Cited
2008
beta-site APP cleaving enzyme-1 (BACE1), the rate-limiting enzyme for beta-amyloid (Abeta) production, is elevated in Alzheimer's… (More)
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Highly Cited
2007
Highly Cited
2007
Elevated brain glutamate with activation of neuronal glutamate receptors accompanies neurological disorders, such as epilepsy and… (More)
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2006
2006
The drug salubrinal has been identified as an inhibitor of phosphatases that act on the eukaryotic translation initiation factor… (More)
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Highly Cited
2005
Highly Cited
2005
Most protein phosphatases have little intrinsic substrate specificity, making selective pharmacological inhibition of specific… (More)
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Highly Cited
2005
Highly Cited
2005
Parkinson's disease (PD) is a neurodegenerative movement disorder characterized by selective loss of dopaminergic neurons and the… (More)
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