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rufloxacin

Known as: 9-fluoro-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]thiazino[2,3,4-ij]quinoline-6-carboxylic acid, 9-fluoro-10-(N-(4'-methyl)piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido(1,2,3de)-1,4-benzothiazine-6-carboxylic acid 
 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

FluoroquinolonesTopoisomerase II Inhibitors

Narrower (2)

MF 934rufloxacin hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
A Mucoadhesive Polymer Extracted from Tamarind Seed Improves the Intraocular Penetration and Efficacy of Rufloxacin in Topical Treatment of Experimental Bacterial Keratitis
ABSTRACT Bacterial keratitis is a serious infectious ocular disease requiring prompt treatment to prevent frequent and severe… Expand
Highly Cited
2004
Highly Cited
2004
Daily Norfloxacin Is More Effective Than Weekly Rufloxacin in Prevention of Spontaneous Bacterial Peritonitis Recurrence
Our aim was to compare weekly rufloxacin with daily norfloxacin in the secondary prophylaxis of spontaneous bacterial peritonitis… Expand
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Highly Cited
2004
Highly Cited
2004
Biofilm Formation by Stenotrophomonas maltophilia: Modulation by Quinolones, Trimethoprim-Sulfamethoxazole, and Ceftazidime
ABSTRACT We investigated the in vitro effects of seven fluoroquinolones (ciprofloxacin, grepafloxacin, levofloxacin, moxifloxacin… Expand
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2003
2003
Photochemical properties of ofloxacin involved in oxidative DNA damage: a comparison with rufloxacin.
Photodegradation of ofloxacin (OFX) under aerobic conditions gives rise to N-demethylation, mainly involving coupling of radical… Expand
2002
2002
Type II guanine oxidation photoinduced by the antibacterial fluoroquinolone Rufloxacin in isolated DNA and in 2'-deoxyguanosine.
The role played by type I (radical) and type II (singlet oxygen) mechanisms in the Rufloxacin (RFX)-photoinduced production of 8… Expand
1999
1999
Molecular Mechanisms of Photosensitization Induced by Drugs XII. Photochemistry and Photosensitization of Rufloxacin: An Unusual Photodegradation Path for the Antibacterials Containing a…
Abstract The UVA irradiation of 9‐fluoro‐2,3‐dihydro‐10‐4′‐meth‐yl‐l'‐piperazinyl‐7‐oxo‐7H‐pyrido[l,2,3‐de]‐l,4‐benzo‐thiazine‐6… Expand
1995
1995
Rufloxacin once daily versus ciprofloxacin twice daily in the treatment of patients with acute uncomplicated pyelonephritis.
PURPOSE We compare the bacteriological and clinical efficacy of rufloxacin and ciprofloxacin in patients with acute uncomplicated… Expand
1992
1992
The in-vitro activity of two new quinolones: rufloxacin and MF 961.
The in-vitro activity of two new quinolone antimicrobials, rufloxacin and MF 961, together with the desmethylated metabolite of… Expand
1992
1992
Multiple-dose pharmacokinetics and safety of rufloxacin in normal volunteers.
The pharmacokinetics and safety of rufloxacin were evaluated in a double-blind, placebo-controlled study. Two groups of 16… Expand
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1991
1991
Inter- and intrasubject variabilities in the pharmacokinetics of rufloxacin after single oral administration to healthy volunteers.
Rufloxacin is a new long-acting, once-daily quinolone antibacterial agent. We evaluated inter- and intrasubject variations in… Expand
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