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rufloxacin

Known as: 9-fluoro-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]thiazino[2,3,4-ij]quinoline-6-carboxylic acid, 9-fluoro-10-(N-(4'-methyl)piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido(1,2,3de)-1,4-benzothiazine-6-carboxylic acid 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

FluoroquinolonesTopoisomerase II Inhibitors

Narrower (2)

MF 934rufloxacin hydrochloride

Papers overview

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Highly Cited
2003
Highly Cited
2003
Photochemical properties of ofloxacin involved in oxidative DNA damage: a comparison with rufloxacin.
Photodegradation of ofloxacin (OFX) under aerobic conditions gives rise to N-demethylation, mainly involving coupling of radical… 
Highly Cited
2002
Highly Cited
2002
Daily Norfloxacin Is More Effective Than Weekly Rufloxacin in Prevention of Spontaneous Bacterial Peritonitis Recurrence
Our aim was to compare weekly rufloxacin with daily norfloxacin in the secondary prophylaxis of spontaneous bacterial peritonitis… 
2002
2002
Type II guanine oxidation photoinduced by the antibacterial fluoroquinolone Rufloxacin in isolated DNA and in 2'-deoxyguanosine.
The role played by type I (radical) and type II (singlet oxygen) mechanisms in the Rufloxacin (RFX)-photoinduced production of 8… 
Highly Cited
1999
Highly Cited
1999
Effects of Novel 6-Desfluoroquinolones and Classic Quinolones on Pentylenetetrazole-Induced Seizures in Mice
ABSTRACT There have been several reports that convulsions, although rare, occur in patients who receive fluoroquinolones. In this… 
1998
1998
Determination of protein binding of gyrase inhibitors by means of continuous ultrafiltration.
1994
1994
Effects of some quinolones on imipenem-induced seizures in DBA/2 mice.
Review
1993
Review
1993
Pharmacokinetics of gyrase inhibitors, Part 2: Renal and hepatic elimination pathways and drug interactions.
This article focuses on the relationship of the physicochemical properties of gyrase inhibitors to their hepatic and renal… 
1992
1992
Multiple-dose pharmacokinetics and safety of rufloxacin in normal volunteers
The pharmacokinetics and safety of rufloxacin were evaluated in a double-blind, placebo-controlled study. Two groups of 16… 
1991
1991
Inter- and intrasubject variabilities in the pharmacokinetics of rufloxacin after single oral administration to healthy volunteers
Rufloxacin is a new long-acting, once-daily quinolone antibacterial agent. We evaluated inter- and intrasubject variations in… 
1991
1991
Pharmacokinetics and tissue penetration of rufloxacin, a long acting quinolone antimicrobial agent.
The pharmacokinetics of rufloxacin after a single 400 mg oral dose were studied in eight volunteers, measuring plasma… 
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