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rufloxacin

Known as: 9-fluoro-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]thiazino[2,3,4-ij]quinoline-6-carboxylic acid, 9-fluoro-10-(N-(4'-methyl)piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido(1,2,3de)-1,4-benzothiazine-6-carboxylic acid 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

FluoroquinolonesTopoisomerase II Inhibitors

Narrower (2)

MF 934rufloxacin hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Rufloxacin-induced photosensitization in yeast
The fluoroquinolone Rufloxacin (RFX) is active as specific inhibitor of bacterial gyrase. The adverse effects of the… 
Highly Cited
2003
Highly Cited
2003
Photochemical properties of ofloxacin involved in oxidative DNA damage: a comparison with rufloxacin.
Photodegradation of ofloxacin (OFX) under aerobic conditions gives rise to N-demethylation, mainly involving coupling of radical… 
2002
2002
Type II guanine oxidation photoinduced by the antibacterial fluoroquinolone Rufloxacin in isolated DNA and in 2'-deoxyguanosine.
The role played by type I (radical) and type II (singlet oxygen) mechanisms in the Rufloxacin (RFX)-photoinduced production of 8… 
2002
2002
Photoinduced N-Demethylation of Rufloxacin and its Methyl Ester Under Aerobic Conditions¶
Abstract Irradiation of rufloxacin (RF) under aerobic conditions gives rise to N-demethylation of the piperazinyl ring, which is… 
1994
1994
Effects of some quinolones on imipenem-induced seizures in DBA/2 mice.
1993
1993
The penetration of rufloxacin into sites of potential infection in the respiratory tract.
The concentrations of rufloxacin in the bronchial mucosal, pulmonary epithelial lining fluid and alveolar macrophages were… 
1993
1993
Pharmacokinetics of rufloxacin in patients with impaired renal function
The pharmacokinetics of rufloxacin were investigated in normal subjects and in patients with various degrees of renal failure… 
1991
1991
Inter- and intrasubject variabilities in the pharmacokinetics of rufloxacin after single oral administration to healthy volunteers
Rufloxacin is a new long-acting, once-daily quinolone antibacterial agent. We evaluated inter- and intrasubject variations in… 
1991
1991
Pharmacokinetics and tissue penetration of rufloxacin, a long acting quinolone antimicrobial agent.
The pharmacokinetics of rufloxacin after a single 400 mg oral dose were studied in eight volunteers, measuring plasma… 
1991
1991
Pharmacokinetics of rufloxacin in healthy volunteers after repeated oral doses.
Rufloxacin is a new broad-spectrum fluoroquinolone antibacterial agent. The pharmacokinetics and safety of rufloxacin were… 
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