rotundic acid
National Institutes of Health
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Rotundic acid (RA) is a major triterpene constituent in the barks of Ilex rotunda Thunb, which have been widely used to make…
Hepatocellular carcinoma (HCC) is the fourth largest cause of cancer-related deaths worldwide with limited therapeutic…
BackgroundTuberculosis is a deadly disease caused by Mycobacterium species. The use of medicinal plants is an ancient global…
Although radiation therapy is a powerful anticancer modality, radiation- induced stress response and gene expression with…
In the present study, the functions and mechanisms of rotundic acid (RA) underlying its induction of apoptosis in caspase-3…
Abstract Context: Hedyotis pilulifera (Pit.) T.N. Ninh (Rubiaceae) has been used in Vietnamese ethnomedicine; the methanol…
AIM AND OBJECTIVE
Kelch like ECH-associated protein 1 (Keap1) and Nuclear factor-E2 related factor 2 (Nrf2) binding is a key step…
Six novel rotundic acid (RA, 1) derivatives 4a-4f modified at the 28-COOH position were synthesized, and their structures were…
A novel indole alkaloid, nauclefolinine ( 1 ) and five known triterpenic compounds, rotundic acid ( 2 ), a -L-rhamnoquinovic acid…
A new triterpene acid, named barbinervic acid (I) has been isolated from the leaves of Clethra barbinervis SIEB. et ZUCC. and…