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rontalizumab
Known as:
Immunoglobulin G1, anti-(human interferons alpha type); humanized mouse monoclonal rhuMAB IFNalpha gamma1 heavy chain (des-CH3(sup 107)K, CH1(sup 97)R>K-IGHG1*03) (220-218')-disulfide with humanized mouse monoclonal rhuMAB IFNalpha kappa light chain, dimer (226-226'':229-229'')-bisdisulfide
, RhuMAb IFNalpha
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Antibodies, Monoclonal, Humanized
antigen binding
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
I9 Clinical trials with IFN blockers
R. Furie
2020
Corpus ID: 216326341
Background Type I interferon (IFN) pathway activation has long been demonstrated in patients with systemic lupus erythematosus…
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Review
2016
Review
2016
Why, why, why de-lupus (does so badly in clinical trials)
D. Isenberg
,
J. Merrill
Expert Review of Clinical Immunology
2016
Corpus ID: 8875017
There is abundant evidence that B-lymphocytes play a major role in the development of lupus (reviewed in [1]). It thus seemed…
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Review
2016
Review
2016
FRI0350 The IFN Biomarker Siglec1 Indicates Extraglandular Manifestation in Primary Sjögren's Syndrome
T. Rose
,
F. Szelinski
,
G. Burmester
,
F. Hiepe
,
R. Biesen
,
T. Dörner
2016
Corpus ID: 78952115
Background Over the last decades evidence of an activated type I interferon (IFN) system in the pathogenesis of different…
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2009
2009
Treatment of Chronic Hepatitis C in a Patient Affected by Systemic Sclerosis
G. Poggi
,
L. Villani
,
+4 authors
G. Bernardo
Gastroenterology Research and Practice
2009
Corpus ID: 17365619
The currently recommended treatment for patients infected with hepatitis C virus (HCV) is pegilated interferon α (IFN α) plus…
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2001
2001
Astrocyte-Targeted Expression of Interleukin-3 and Interferon-α Causes Region-Specific Changes in Metallothionein Expression in the Brain
M. Giralt
,
J. Carrasco
,
+4 authors
J. Hidalgo
Experimental Neurology
2001
Corpus ID: 6211919
Transgenic mice expressing IL-3 and IFN-alpha under the regulatory control of the GFAP gene promoter (GFAP-IL3 and GFAP-IFNalpha…
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2000
2000
Opening the flood gates: interferon-alpha treatment for Sjögren's syndrome.
S. Shiozawa
,
J. Cummins
,
P. Fox
BioDrugs
2000
Corpus ID: 6664942
Interferon (IFN)-alpha is the main IFN produced in response to viral infection. Low levels of IFNalpha can be detected in nasal…
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2000
2000
Randomized controlled trial of twice-a-day administration of natural interferon beta for chronic hepatitis C.
Yoshioka
,
Yano
,
+8 authors
Kakumu
Hepatology Research
2000
Corpus ID: 24423082
We conducted a randomized controlled trial to assess the efficacy of twice-a-day administration of natural interferon beta…
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2000
2000
Interferon-alpha alone versus interferon-alpha plus ribavirin in patients with chronic hepatitis C not responding to previous interferon-alpha treatment.
S. Tripi
,
G. Di Gaetano
,
+5 authors
G. Montalto
BioDrugs
2000
Corpus ID: 37763209
OBJECTIVE To study the effects of monotherapy with leucocyte interferon-alpha (IFNalpha) versus IFNalpha + ribavirin in patients…
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