riociguat

Known as: Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminate, Riociguatum 
 

Topic mentions per year

Topic mentions per year

2009-2017
0102020092017

Papers overview

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2016
2016
BACKGROUND Pulmonary arterial hypertension is a chronic disease associated with poor long-term outcomes. Identifying predictors… (More)
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2015
Highly Cited
2015
Riociguat is a soluble, guanylate cyclase stimulator, approved for pulmonary arterial hypertension. In the 12-week PATENT-1 study… (More)
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2015
2015
PATENT PLUS evaluated the safety and efficacy of riociguat in combination with sildenafil in pulmonary arterial hypertension… (More)
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2014
2014
BACKGROUND Deficient nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate signaling results from endothelial… (More)
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2013
2013
BACKGROUND Pulmonary hypertension caused by systolic left ventricular dysfunction is associated with significant morbidity and… (More)
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2013
2013
We assessed the safety, tolerability and preliminary efficacy of riociguat, a soluble guanylate cyclase stimulator, in patients… (More)
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2012
2012
AIMS Pulmonary hypertension (PH) due to systolic left ventricular dysfunction (PH-sLVD) frequently complicates heart failure (HF… (More)
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2011
2011
BACKGROUND The nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic guanosine monophosphate (cGMP) signal-transduction… (More)
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2011
2011
Riociguat (BAY 63-2521) and warfarin are likely to be used concomitantly to treat pulmonary hypertension. The aim of this double… (More)
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Highly Cited
2009
Highly Cited
2009
Pulmonary hypertension (PH) is associated with impaired production of the vasodilator nitric oxide (NO). Riociguat (BAY 63-2521… (More)
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