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rimonabant

Known as: 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide, N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
CONTEXT Abdominal obesity is associated with metabolic abnormalities and increased risk of atherosclerotic cardiovascular disease… Expand
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Review
2007
Review
2007
BACKGROUND Since the prevalence of obesity continues to increase, there is a demand for effective and safe anti-obesity agents… Expand
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Review
2007
Review
2007
Antiobesity treatment is recommended for selected patients in whom lifestyle modification is unsuccessful. Two antiobesity drugs… Expand
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Highly Cited
2007
Highly Cited
2007
This study investigated the effects of rimonabant (SR141716), an antagonist of the cannabinoid receptor type 1 (CB1), on obesity… Expand
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Highly Cited
2006
Highly Cited
2006
CONTEXT Rimonabant, a selective cannabinoid-1 receptor blocker, may reduce body weight and improve cardiometabolic risk factors… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Rimonabant, a selective cannabinoid type 1 receptor blocker, reduces bodyweight and improves cardiovascular and… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Rimonabant, a selective cannabinoid-1 receptor (CB1) blocker, has been shown to reduce body weight and improve… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND In animal models, cannabinoid-1 receptor (CB1) blockade produces a lean phenotype, with resistance to diet-induced… Expand
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Highly Cited
2005
Highly Cited
2005
We investigated the molecular events involved in the long‐lasting reduction of adipose mass by the selective CB1 antagonist… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The endocannabinoid system has been implicated in the modulation of emotional processes. METHODS These experiments… Expand
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