rimonabant

Known as: 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide, N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Blockade of the endocannabinoid receptor reduces obesity and improves metabolic abnormalities such as triglycerides… (More)
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Highly Cited
2008
Highly Cited
2008
CONTEXT Abdominal obesity is associated with metabolic abnormalities and increased risk of atherosclerotic cardiovascular disease… (More)
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Review
2007
Review
2007
Antiobesity treatment is recommended for selected patients in whom lifestyle modification is unsuccessful. Two antiobesity drugs… (More)
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Highly Cited
2007
Highly Cited
2007
This study investigated the effects of rimonabant (SR141716), an antagonist of the cannabinoid receptor type 1 (CB1), on obesity… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Rimonabant, a selective cannabinoid type 1 receptor blocker, reduces bodyweight and improves cardiovascular and… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT Rimonabant, a selective cannabinoid-1 receptor blocker, may reduce body weight and improve cardiometabolic risk factors… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND In animal models, cannabinoid-1 receptor (CB1) blockade produces a lean phenotype, with resistance to diet-induced… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Rimonabant, a selective cannabinoid-1 receptor (CB1) blocker, has been shown to reduce body weight and improve… (More)
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Highly Cited
2005
Highly Cited
2005
Conditioned stimuli are important for nicotine dependence and may trigger craving and relapse after prolonged nicotine abstinence… (More)
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Highly Cited
2004
Highly Cited
2004
The effects of Rimonabant (SR141716), an antagonist at cannabinoid CB1 receptors, were evaluated in animal models for subjective… (More)
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