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rhodopsin kinase

Known as: G Protein Coupled Receptor Kinase 1, Opsin Kinase, Kinase, Rhodopsin 
A PROTEIN-SERINE-THREONINE KINASE that is found in PHOTORECEPTOR CELLS. It mediates light-dependent PHOSPHORYLATION of RHODOPSIN and plays an… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Mutations in Rpe65 disrupt synthesis of the opsin chromophore ligand 11-cis-retinal and cause Leber congenital amaurosis (LCA), a… Expand
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Highly Cited
1999
Highly Cited
1999
Phosphorylation is thought to be an essential first step in the prompt deactivation of photoexcited rhodopsin. In vitro, the… Expand
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Highly Cited
1993
Highly Cited
1993
Rhodopsin phosphorylation is a key event in the deactivation of this G-protein-coupled receptor. Rhodopsin kinase mediates the… Expand
Review
1992
Review
1992
Rhodopsin is the photoreceptor protein in rod cells of the vertebrate retina and the first member of the class of G protein… Expand
Highly Cited
1992
Highly Cited
1992
The primary structure of bovine rhodopsin kinase (RK), which phosphorylates light-activated rhodopsin (Rho*), terminates with the… Expand
Highly Cited
1992
Highly Cited
1992
We have shown by intravitreal injection of [3H]mevalonolactone that a 65 kDa protein in rat photoreceptors is posttranslationally… Expand
Highly Cited
1991
Highly Cited
1991
Rhodopsin kinase (RK) catalyzes the phosphorylation of rhodopsin (Rho) as one of the steps in quenching photoactivated Rho. In… Expand
Highly Cited
1991
Highly Cited
1991
Light-dependent deactivation of rhodopsin as well as homologous desensitization of beta-adrenergic receptors involves receptor… Expand
Highly Cited
1988
Highly Cited
1988
Rhodopsin kinase was purified to near homogeneity by affinity binding to light-exposed rod cell outer segment membranes, followed… Expand
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Highly Cited
1986
Highly Cited
1986
The structural components involved in transduction of extracellular signals as diverse as a photon of light impinging on the… Expand