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rhodopsin kinase

Known as: G Protein Coupled Receptor Kinase 1, Opsin Kinase, Kinase, Rhodopsin 
A PROTEIN-SERINE-THREONINE KINASE that is found in PHOTORECEPTOR CELLS. It mediates light-dependent PHOSPHORYLATION of RHODOPSIN and plays an… Expand
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Studies in the 1930s demonstrated that birds possess photoreceptors that are located within the hypothalamus and regulate… Expand
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Highly Cited
2006
Highly Cited
2006
Signaling through G protein-coupled receptors (GPCRs) underlies many cellular processes, yet it is not known which molecules… Expand
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Highly Cited
2003
Highly Cited
2003
Mutations in Rpe65 disrupt synthesis of the opsin chromophore ligand 11-cis-retinal and cause Leber congenital amaurosis (LCA), a… Expand
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Highly Cited
1999
Highly Cited
1999
Phosphorylation is thought to be an essential first step in the prompt deactivation of photoexcited rhodopsin. In vitro, the… Expand
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Highly Cited
1995
Highly Cited
1995
Mutation of Gly90, Glu113, Ala292, and Lys296 in the visual pigment rhodopsin constitutively activates the protein for activation… Expand
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Highly Cited
1993
Highly Cited
1993
Rhodopsin phosphorylation is a key event in the deactivation of this G-protein-coupled receptor. Rhodopsin kinase mediates the… Expand
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Review
1992
Review
1992
Rhodopsin is the photoreceptor protein in rod cells of the vertebrate retina and the first member of the class of G protein… Expand
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Highly Cited
1992
Highly Cited
1992
The primary structure of bovine rhodopsin kinase (RK), which phosphorylates light-activated rhodopsin (Rho*), terminates with the… Expand
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Highly Cited
1991
Highly Cited
1991
Rhodopsin kinase (RK) catalyzes the phosphorylation of rhodopsin (Rho) as one of the steps in quenching photoactivated Rho. In… Expand
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Highly Cited
1991
Highly Cited
1991
Light-dependent deactivation of rhodopsin as well as homologous desensitization of beta-adrenergic receptors involves receptor… Expand
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