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rhodopsin kinase

Known as: G Protein Coupled Receptor Kinase 1, Opsin Kinase, Kinase, Rhodopsin 
A PROTEIN-SERINE-THREONINE KINASE that is found in PHOTORECEPTOR CELLS. It mediates light-dependent PHOSPHORYLATION of RHODOPSIN and plays an… 
National Institutes of Health

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GRK1 geneIn BloodProcess of secretionantagonists & inhibitors

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RHOK protein, human

Papers overview

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Highly Cited
2009
Highly Cited
2009
VA Opsin-Based Photoreceptors in the Hypothalamus of Birds
Highly Cited
2006
Highly Cited
2006
RGS Expression Rate-Limits Recovery of Rod Photoresponses
Highly Cited
2003
Highly Cited
2003
Spontaneous activity of opsin apoprotein is a cause of Leber congenital amaurosis
Mutations in Rpe65 disrupt synthesis of the opsin chromophore ligand 11-cis-retinal and cause Leber congenital amaurosis (LCA), a… 
Highly Cited
1999
Highly Cited
1999
Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase.
Phosphorylation is thought to be an essential first step in the prompt deactivation of photoexcited rhodopsin. In vitro, the… 
Highly Cited
1995
Highly Cited
1995
Constitutive activation of opsin: interaction of mutants with rhodopsin kinase and arrestin.
Mutation of Gly90, Glu113, Ala292, and Lys296 in the visual pigment rhodopsin constitutively activates the protein for activation… 
Highly Cited
1993
Highly Cited
1993
Interaction between photoactivated rhodopsin and its kinase: stability and kinetics of complex formation.
Rhodopsin phosphorylation is a key event in the deactivation of this G-protein-coupled receptor. Rhodopsin kinase mediates the… 
Review
1992
Review
1992
Rhodopsin and phototransduction: a model system for G protein‐linked receptors
Rhodopsin is the photoreceptor protein in rod cells of the vertebrate retina and the first member of the class of G protein… 
Highly Cited
1991
Highly Cited
1991
Regulation of rhodopsin kinase by autophosphorylation.
Rhodopsin kinase (RK) catalyzes the phosphorylation of rhodopsin (Rho) as one of the steps in quenching photoactivated Rho. In… 
Highly Cited
1991
Highly Cited
1991
The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase.
Light-dependent deactivation of rhodopsin as well as homologous desensitization of beta-adrenergic receptors involves receptor… 
Highly Cited
1986
Highly Cited
1986
Light-dependent phosphorylation of rhodopsin by β-adrenergic receptor kinase
The structural components involved in transduction of extracellular signals as diverse as a photon of light impinging on the… 
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