rhodopsin kinase

Known as: G Protein Coupled Receptor Kinase 1, Opsin Kinase, Kinase, Rhodopsin 
A PROTEIN-SERINE-THREONINE KINASE that is found in PHOTORECEPTOR CELLS. It mediates light-dependent PHOSPHORYLATION of RHODOPSIN and plays an… (More)
National Institutes of Health

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RHOK protein, human

Papers overview

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2012
2012
Modulation of mouse rod response decay by rhodopsin kinase and recoverin.
Light isomerizes 11-cis-retinal in a retinal rod and produces an active form of rhodopsin (Rh*) that binds to the G-protein… (More)
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Highly Cited
2009
Highly Cited
2009
VA Opsin-Based Photoreceptors in the Hypothalamus of Birds
Studies in the 1930s demonstrated that birds possess photoreceptors that are located within the hypothalamus and regulate… (More)
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Highly Cited
2008
Highly Cited
2008
Jellyfish vision starts with cAMP signaling mediated by opsin-G(s) cascade.
Light sensing starts with phototransduction in photoreceptor cells. The phototransduction cascade has diverged in different… (More)
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Highly Cited
2006
Highly Cited
2006
RGS Expression Rate-Limits Recovery of Rod Photoresponses
Signaling through G protein-coupled receptors (GPCRs) underlies many cellular processes, yet it is not known which molecules… (More)
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Highly Cited
2003
Highly Cited
2003
Spontaneous activity of opsin apoprotein is a cause of Leber congenital amaurosis
Mutations in Rpe65 disrupt synthesis of the opsin chromophore ligand 11-cis-retinal and cause Leber congenital amaurosis (LCA), a… (More)
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Highly Cited
1999
Highly Cited
1999
Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase.
Phosphorylation is thought to be an essential first step in the prompt deactivation of photoexcited rhodopsin. In vitro, the… (More)
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1999
1999
Structure and function in rhodopsin: effects of disulfide cross-links in the cytoplasmic face of rhodopsin on transducin activation and phosphorylation by rhodopsin kinase.
Six rhodopsin mutants containing disulfide cross-links between different cytoplasmic regions were prepared: disulfide bond 1… (More)
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1995
1995
Rhodopsin mutants discriminate sites important for the activation of rhodopsin kinase and Gt.
The cytoplasmic loops of rhodopsin, the rod cell photoreceptor, play important regulatory roles in the activation of both… (More)
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1992
1992
Isoprenylation of a protein kinase. Requirement of farnesylation/alpha-carboxyl methylation for full enzymatic activity of rhodopsin kinase.
The primary structure of bovine rhodopsin kinase (RK), which phosphorylates light-activated rhodopsin (Rho*), terminates with the… (More)
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1988
1988
Purification and characterization of rhodopsin kinase.
Rhodopsin kinase was purified to near homogeneity by affinity binding to light-exposed rod cell outer segment membranes, followed… (More)
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