rhizoxin

A macrocyclic lactone. Rhizoxin binds to tubulin and inhibits microtubule assembly, thereby inducing cytotoxicity. This agent also may inhibit… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2016
051019842016

Papers overview

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2006
2006
The potent antimitotic polyketide macrolide rhizoxin, the causal agent of rice seedling blight, is not produced by the fungus… (More)
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Highly Cited
2005
Highly Cited
2005
A number of plant pathogenic fungi belonging to the genus Rhizopus are infamous for causing rice seedling blight. This plant… (More)
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Highly Cited
1999
Highly Cited
1999
Trypanosoma brucei has a single nucleus and a single kinetoplast (the mitochondrial genome). Each of these organelles has a… (More)
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Highly Cited
1995
Highly Cited
1995
Trypanosoma brucei has a precisely ordered microtubule cytoskeleton whose morphogenesis is central to cell cycle events such as… (More)
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1992
1992
Rhizoxin is a tubulin-binding cytotoxic compound, isolated from the fungus Rhizopus chinensis, with significant antineoplastic… (More)
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Highly Cited
1991
Highly Cited
1991
Data generated in the new National Cancer Institute drug evaluation program, which is based on inhibition of cell growth in 60… (More)
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1990
1990
Rhizoxin is an antitumor drug prepared from the fungus Rhizopus chinensis. It is an inhibitor of microtubule assembly and a… (More)
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1987
1987
The binding of rhizoxin, a potent inhibitor of mitosis and in vitro microtubule assembly, to porcine brain tubulin was studied… (More)
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1986
1986
Rhizoxin, isolated from a plant pathogenic fungus which causes rice seedling blight, inhibits the mitosis of the tumor cells in a… (More)
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1984
1984
A new 16-membered macrolide designated as rhizoxin was isolated as a toxin produced by Rhizopus chinensis, the causal agent of… (More)
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