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Tubulin Modulators

Known as: Microtubule Modulators, Modulators, Microtubule, Modulators, Tubulin 
Agents that interact with TUBULIN to inhibit or promote polymerization of MICROTUBULES.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Taxanes are a family of natural products with a broad spectrum of anticancer activity. This activity is mediated by interaction… Expand
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2018
2018
Microtubule inhibitors as chemotherapeutic drugs are widely used for cancer treatment. However, the development of multidrug… Expand
2016
2016
The development of cancer is often accompanied by a loss of the primary cilium, a microtubule-based cellular protrusion that… Expand
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Review
2015
Review
2015
Imidazoles and benzimidazoles are privileged heterocyclic bioactive compounds used with success in the clinical practice of… Expand
2014
2014
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Background: Most cytotoxic agents are often broadly active… Expand
2011
2011
ABSTRACT Previous studies have observed fluorescently labeled HIV particles tracking along microtubule networks for nuclear… Expand
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Review
2008
Review
2008
BACKGROUND Microtubule-stabilising agents typified by the epothilone class of drug have demonstrated promising activity in Phase… Expand
Review
2008
Review
2008
Background: Microtubule-stabilising agents typified by the epothilone class of drug have demonstrated promising activity in Phase… Expand
2000
2000
  • R. Heald
  • Nature Cell Biology
  • 2000
  • Corpus ID: 21092753
Microtubule dynamics are regulated by a diverse array of factors. The net balance of two opposing activities largely determines… Expand
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