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Tubulin Modulators
Known as:
Microtubule Modulators
, Modulators, Microtubule
, Modulators, Tubulin
Agents that interact with TUBULIN to inhibit or promote polymerization of MICROTUBULES.
National Institutes of Health
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39 relations
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2-methoxyestradiol
Albendazole
Benomyl
Colchicine
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In Blood
Microtubule Inhibitor [EPC]
Microtubules
agonists
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site
Y. Lo
,
Olga Cormier
,
+4 authors
R. Altman
Nature Communications
2019
Corpus ID: 70350371
Taxanes are a family of natural products with a broad spectrum of anticancer activity. This activity is mediated by interaction…
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2019
2019
Faculty Opinions recommendation of Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site.
G. Rastelli
Faculty Opinions – Post-Publication Peer Review…
2019
Corpus ID: 155292023
2016
2016
Identification of drugs that restore primary cilium expression in cancer cells
N. Khan
,
N. Willemarck
,
+11 authors
J. Swinnen
Oncotarget
2016
Corpus ID: 6575756
The development of cancer is often accompanied by a loss of the primary cilium, a microtubule-based cellular protrusion that…
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Review
2015
Review
2015
Imidazoles and benzimidazoles as tubulin-modulators for anti-cancer therapy.
F. Torres
,
M. E. García-Rubiño
,
+4 authors
J. Campos
Current medicinal chemistry
2015
Corpus ID: 35328731
Imidazoles and benzimidazoles are privileged heterocyclic bioactive compounds used with success in the clinical practice of…
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2011
2011
Effects of Microtubule Modulators on HIV-1 Infection of Transformed and Resting CD4 T Cells
Alyson C Yoder
,
Jia Guo
,
Dongyang Yu
,
Zongqiang Cui
,
Xian-En Zhang
,
Yuntao Wu
Journal of Virology
2011
Corpus ID: 41140414
ABSTRACT Previous studies have observed fluorescently labeled HIV particles tracking along microtubule networks for nuclear…
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Review
2011
Review
2011
RASSF1A: Not a prototypical Ras effector.
M. Gordon
,
S. Baksh
Small GTPases
2011
Corpus ID: 38420829
The Ras association domain family (RASSF) of genes are commonly silenced by promoter specific methylation in human cancers. After…
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Review
2010
Review
2010
Still entangled: assembly of the central spindle by multiple microtubule modulators.
M. Douglas
,
M. Mishima
Seminars in cell & developmental biology
2010
Corpus ID: 5524319
Review
2008
Review
2008
Epothilones and new analogues of the microtubule modulators in taxane-resistant disease.
M. Harrison
,
C. Swanton
Expert opinion on investigational drugs
2008
Corpus ID: 23594344
BACKGROUND Microtubule-stabilising agents typified by the epothilone class of drug have demonstrated promising activity in Phase…
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Review
2008
Review
2008
Epothilones and new analogues of the microtubule modulators in taxane-resistant disease
M. Harrison
,
C. Swanton
2008
Corpus ID: 72409072
Background: Microtubule-stabilising agents typified by the epothilone class of drug have demonstrated promising activity in Phase…
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Review
2006
Review
2006
Pharmacological strategies for the prevention of Alzheimer’s disease
P. Doraiswamy
,
G. Xiong
Expert opinion on pharmacotherapy
2006
Corpus ID: 37276697
This review examines key pharmacological strategies that have been clinically studied for the primary or secondary prevention of…
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