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Tubulin Modulators

Known as: Microtubule Modulators, Modulators, Microtubule, Modulators, Tubulin 
Agents that interact with TUBULIN to inhibit or promote polymerization of MICROTUBULES.
National Institutes of Health

Papers overview

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2019
2019
Taxanes are a family of natural products with a broad spectrum of anticancer activity. This activity is mediated by interaction… Expand
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2018
2018
Microtubule inhibitors, as chemotherapeutic drugs, are widely used for cancer treatment in clinic. However, the development of… Expand
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2016
2016
The development of cancer is often accompanied by a loss of the primary cilium, a microtubule-based cellular protrusion that… Expand
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Review
2015
Review
2015
Imidazoles and benzimidazoles are privileged heterocyclic bioactive compounds used with success in the clinical practice of… Expand
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2014
2014
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Background: Most cytotoxic agents are often broadly active… Expand
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2011
2011
Previous studies have observed fluorescently labeled HIV particles tracking along microtubule networks for nuclear localization… Expand
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Review
2008
Review
2008
BACKGROUND Microtubule-stabilising agents typified by the epothilone class of drug have demonstrated promising activity in Phase… Expand
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Review
2008
Review
2008
Background: Microtubule-stabilising agents typified by the epothilone class of drug have demonstrated promising activity in Phase… Expand
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2000
2000
Microtubule dynamics are regulated by a diverse array of factors. The net balance of two opposing activities largely determines… Expand
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