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2-methoxyestradiol

Known as: 2-Methoxy Estradiol, 2-MeE2, 2 methoxyestradiol 
An orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
AbstractThe authors describe carbon system formulation and simulation characteristics of two new global coupled carbon–climate… Expand
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Highly Cited
2011
Highly Cited
2011
Abstract. An earth system model (MIROC-ESM 2010) is fully described in terms of each model component and their interactions… Expand
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Highly Cited
2011
Highly Cited
2011
Abstract. The scientific understanding of the Earth's climate system, including the central question of how the climate system is… Expand
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Highly Cited
2011
Highly Cited
2011
We report here a general approach to using multifunctional poly(amidoamine) (PAMAM) dendrimer-based platform to encapsulate a… Expand
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Highly Cited
2009
Highly Cited
2009
Autophagy is involved in human diseases and is regulated by reactive oxygen species (ROS) including superoxide (O2•−) and… Expand
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Highly Cited
2008
Highly Cited
2008
Despite intense investigation, mechanisms that facilitate the emergence of the pre-eclampsia phenotype in women are still unknown… Expand
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Review
2003
Review
2003
Estrogens occurring naturally in the body are metabolized to catecholestrogens (2- and 4-hydroxyestradiol) by the cytochrome P450… Expand
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Highly Cited
1997
Highly Cited
1997
2-Methoxyestradiol (2-ME), an endogenous estrogen metabolite which disrupts microtubule function, has been shown to inhibit… Expand
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Highly Cited
1994
Highly Cited
1994
THE formation of new blood vessels (angiogenesis) is critical for the growth of tumours1–3 and is a dominant feature in various… Expand
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Highly Cited
1994
Highly Cited
1994
A metabolite of estradiol, 2-methoxyestradiol (2ME), inhibits angiogenesis in the chicken embryo chorioallantoic membrane assay… Expand
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