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2-methoxyestradiol

Known as: 2-Methoxy Estradiol, 2-MeE2, 2 methoxyestradiol 
An orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial… 
National Institutes of Health

Related topics

Related topics

14 relations

Narrower (2)

2-methoxyestradiol-17 betaPanzem
Angiogenesis InhibitionEndothelial CellsInhibition of Cell ProliferationMicrotubule Process

Broader (2)

EstradiolTubulin Modulators

Papers overview

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Highly Cited
2008
Highly Cited
2008
Evidence that the COMTVal158Met polymorphism moderates sensitivity to stress in psychosis: An experience‐sampling study
Gene–environment interactions involving the catechol‐O‐methyltransferase Val158Met polymorphism (COMTVal158Met) have been… 
Highly Cited
2005
Highly Cited
2005
Hole inflation and tapering of stock photonic crystal fibres.
We report controlled hole expansion in photonic crystal fibres (PCFs) by heating the fibre while the holes were pressurised. This… 
Highly Cited
2005
Highly Cited
2005
Effective SINR approach of link to system mapping in OFDM/multi-carrier mobile network
This paper presents approaches of link to system mapping for OFDM/multi-carrier mobile communications systems. Mainly, the… 
Highly Cited
2004
Highly Cited
2004
Link error prediction methods for multicarrier systems
Multicarrier modulations such as OFDM with adaptive modulation and coding (AMC) are well suited for high data rate broadband… 
Highly Cited
2003
Highly Cited
2003
Novel 2-methoxyestradiol analogues with antitumor activity.
2-Methoxyestradiol (2-ME2) is a natural estrogen metabolite that, while devoid of estrogenic effects, has both antiangiogenic and… 
Highly Cited
2002
Highly Cited
2002
Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia
Highly Cited
2000
Highly Cited
2000
Comparison of 2‐methoxyestradiol‐induced, docetaxel‐induced, and paclitaxel‐induced apoptosis in hepatoma cells and its correlation with reactive oxygen species
Previously, the authors observed that paclitaxel treatment of hepatoma cells resulted in differential cytotoxicity. Whether other… 
Highly Cited
1998
Highly Cited
1998
2-Methoxyestradiol-induced phosphorylation of Bcl-2: uncoupling from JNK/SAPK activation.
The natural estrogen metabolite 2-methoxyestradiol (2ME) is anti-angiogenic in vivo and a strong growth inhibitor in vitro. The… 
Highly Cited
1977
Highly Cited
1977
Nonspecific activation of murine lymphocytes. I. Proliferation and polyclonal activation induced by 2-mercaptoethanol and alpha- thioglycerol
The effect of 2-mercaptoethanol (2-ME) and alpha-thioglycerol (alpha TG) on proliferation and polyclonal activation of… 
Highly Cited
1976
Highly Cited
1976
Function of 2-mercaptoethanol as a macrophage substitute in the primary immune response in vitro.
The mechanism by which 2-ME acts as a macrophage-substitute for the induction of a primary PFC response to SRC in vitro was… 
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