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reveromycin A

Known as: reveromycin 
National Institutes of Health

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2 relations

Broader (2)

PyransSpiro Compounds

Papers overview

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2015
2015
Reveromycin A Administration Prevents Alveolar Bone Loss in Osteoprotegerin Knockout Mice with Periodontal Disease
Chronic periodontal disease is characterized by alveolar bone loss and inflammatory changes. Reveromycin A (RMA) was recently… 
2014
2014
Structure-Function Analyses of Cytochrome P450revI Involved in Reveromycin A Biosynthesis and Evaluation of the Biological Activity of Its Substrate, Reveromycin T*
Background: Hydroxylation of natural products is a key step for generating structural diversity. Results: The revI gene… 
2012
2012
Effect of Reveromycin A on Experimental Tooth Movement in OPG−/− Mice
In osteoprotegerin-deficient (OPG−/−) mice, osteoclast activity causes bone resorption to outpace bone formation, leading to the… 
Review
2007
Review
2007
Regulation of osteoclast polarization
Osteoclast function consists of several processes: recognition of mineralized tissues, development of ruffled borders and sealing… 
2005
2005
Reveromycin A Inhibits Osteolytic Bone Metastasis of Small-Cell Lung Cancer Cells, SBC-5, through an Antiosteoclastic Activity
Purpose: The purpose of this study was to determine therapeutic effect of a novel antibiotic, reveromycin A, against osteolytic… 
Highly Cited
2002
Highly Cited
2002
Identification of Saccharomyces cerevisiae Isoleucyl-tRNA Synthetase as a Target of the G1-specific Inhibitor Reveromycin A*
To dissect the action mechanism of reveromycin A (RM-A), a G1-specific inhibitor, aSaccharomyces cerevisiae dominant mutant… 
2001
2001
Total synthesis of the epidermal growth factor inhibitor (-)-reveromycin B.
The total synthesis of the epidermal growth factor inhibitor reveromycin B (2) in 25 linear steps from chiral methylene pyran 13… 
Highly Cited
2001
Highly Cited
2001
Cross-talk between Transcriptional Regulators of Multidrug Resistance in Saccharomyces cerevisiae *
Multiple or pleiotropic drug resistance often arises in the yeast Saccharomyces cerevisiae due to genetic alterations of the… 
2000
2000
Stereoselective total synthesis of reveromycin B and C19-epi-reveromycin B.
Our studies toward the total synthesis of the reveromycin family of natural products are described herein. Our synthetic approach… 
2000
2000
Total synthesis of reveromycin A.
The stereoselective total synthesis of reveromycin A (1), a potent inhibitor of eukaryotic cell growth, has been accomplished on… 
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