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response to stem cell factor
Known as:
response to KIT ligand
, response to hematopoietic growth factor KL
, response to SCF
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Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene…
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.
G. Chan
,
Laurene S Cheung
,
+15 authors
B. Braun
Blood
2011
Corpus ID: 29307097
Src homology 2 domain-containing phosphatase 2 (Shp2), encoded by Ptpn11, is a member of the nonreceptor protein-tyrosine…
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Highly Cited
2007
Highly Cited
2007
Critical role for lipid raft-associated Src kinases in activation of PI3K-Akt signalling.
A. Arcaro
,
M. Aubert
,
+6 authors
M. Seckl
Cellular Signalling
2007
Corpus ID: 30186024
Highly Cited
2007
Highly Cited
2007
K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells.
M. E. V. Van Meter
,
E. Diaz-Flores
,
+6 authors
B. Braun
Blood
2007
Corpus ID: 20477090
Defining how cancer-associated mutations perturb signaling networks in stem/progenitor populations that are integral to tumor…
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Highly Cited
2005
Highly Cited
2005
KIT exon 8 mutations associated with core-binding factor (CBF)-acute myeloid leukemia (AML) cause hyperactivation of the receptor in response to stem cell factor.
T. Kohl
,
S. Schnittger
,
J. Ellwart
,
W. Hiddemann
,
K. Spiekermann
Blood
2005
Corpus ID: 22133540
KIT exon 8 mutations are located in the extracellular portion of the receptor and are strongly associated with core-binding…
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Highly Cited
2001
Highly Cited
2001
Signaling through Extracellular Signal-regulated Kinase Is Required for Spermatogonial Proliferative Response to Stem Cell Factor*
S. Dolci
,
M. Pellegrini
,
S. Di Agostino
,
R. Geremia
,
P. Rossi
Journal of Biological Chemistry
2001
Corpus ID: 23823576
In vitro addition of stem cell factor (SCF) to c-kit-expressing A1–A4spermatogonia from prepuberal mice stimulates their…
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Highly Cited
2000
Highly Cited
2000
Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571
Wen-Lan Wang
,
M. E. Healy
,
+7 authors
R. Salgia
Oncogene
2000
Corpus ID: 11098943
Small cell lung cancer (SCLC) is an aggressive cancer characterized by several autocrine growth mechanisms including stem cell…
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Highly Cited
1999
Highly Cited
1999
Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction
J. Lennartsson
,
P. Blume-Jensen
,
M. Hermanson
,
E. Pontén
,
M. Carlberg
,
L. Rönnstrand
Oncogene
1999
Corpus ID: 1334165
In this report we show that Tyr568 and Tyr570 are phosphorylated in vivo in the Kit/stem cell factor receptor (Kit/SCFR…
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Highly Cited
1997
Highly Cited
1997
Stat1 associates with c-kit and is activated in response to stem cell factor.
C. Deberry
,
S. Mou
,
D. Linnekin
Biochemical Journal
1997
Corpus ID: 39798487
Interaction of stem cell factor (SCF), a haematopoietic growth factor, with the receptor tyrosine kinase c-kit leads to…
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Highly Cited
1994
Highly Cited
1994
Rapid exit from G0/G1 phases of cell cycle in response to stem cell factor confers on umbilical cord blood CD34+ cells an enhanced ex vivo expansion potential.
C. Traycoff
,
M. Abboud
,
J. Laver
,
D. Clapp
,
E. Srour
Experimental Hematology
1994
Corpus ID: 9279607
Currently, the most commonly used grafts of progenitor and stem cells for patients undergoing bone marrow transplantation (BMT…
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Highly Cited
1993
Highly Cited
1993
Enhanced proliferative potential in culture of cells from p53-deficient mice.
T. Tsukada
,
Y. Tomooka
,
+7 authors
S. Abe
Oncogene
1993
Corpus ID: 27685013
Normal somatic cells are endowed with limited doubling potential in culture, and the process of immortalization is an inevitable…
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