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replication fork

The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes… 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
DNA replication starts at initiation sites termed replication origins. Metazoan cells contain many more potential origins than… 
Highly Cited
2010
Highly Cited
2010
Accurate response to replication arrest is crucial to preserve genome stability and requires both the ATR and ATM functions. The… 
Highly Cited
2007
Highly Cited
2007
Activation of the checkpoint kinase Rad53 is a critical response to DNA damage that results in stabilization of stalled… 
Highly Cited
2006
Highly Cited
2006
The Saccharomyces cerevisiae DNA helicase Rrm3p is needed for normal fork progression through >1000 discrete sites scattered… 
Highly Cited
2006
Highly Cited
2006
Homozygous inactivation of BLM gives rise to Bloom's syndrome, a disorder associated with genomic instability and cancer… 
Review
2003
Review
2002
Review
2002
To maintain genome integrity in eukaryotes, DNA must be duplicated precisely once before cell division occurs. A process called…