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replisome

A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA… 
National Institutes of Health

Related topics

Related topics

6 relations

Narrower (5)

DNA helicase complexDNA polymerase complexcytoplasmic replisomenuclear replisome

Broader (1)

replication fork

Papers overview

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Review
2017
Review
2017
The architecture and function of the chromatin replication machinery.
Highly Cited
2009
Highly Cited
2009
Replisome progression complex links DNA replication to sister chromatid cohesion in Xenopus egg extracts
Cohesin‐mediated sister chromatid cohesion is established during the S‐phase, and recent studies demonstrate that a cohesin… 
2008
2008
Understanding how the replisome works
  • K. Marians
  • Nature Structural &Molecular Biology
  • 2008
  • Corpus ID: 33833292
Recent papers shed insight into the architecture and dynamics of the components of the bacterial replisome. 
Highly Cited
2007
Highly Cited
2007
The accessory subunit B of DNA polymerase γ is required for mitochondrial replisome function
The mitochondrial replication machinery in human cells includes the DNA polymerase γ holoenzyme and the TWINKLE helicase… 
2005
2005
Interaction between the T4 helicase-loading protein (gp59) and the DNA polymerase (gp43): a locking mechanism to delay replication during replisome assembly.
The T4 helicase-loading protein (gp59) has been proposed to coordinate leading- and lagging-strand DNA synthesis by blocking… 
Highly Cited
2004
Highly Cited
2004
Checkpoint-mediated control of replisome–fork association and signalling in response to replication pausing
The replication checkpoint controls the integrity of replicating chromosomes by stabilizing stalled forks, thus preventing the… 
Highly Cited
1994
Highly Cited
1994
Analysis of cis and trans acting elements required for the initiation of DNA replication in the Bacillus subtilis bacteriophage SPP1.
Highly Cited
1991
Highly Cited
1991
A RecA protein mutant deficient in its interaction with the UmuDC complex.
Review
1988
Review
1988
Functions of the DnaA protein of Escherichia coli in replication and transcription.
1984
1984
Evidence for participation of a multiprotein complex in yeast DNA replication in vitro.
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