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ravuconazole

Known as: 3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol, p-(2-((alphaR,betaR)-2,4-Difluoro-beta-hydroxy-alpha-methyl-beta-(1H-1,2,4-triazol-1-ylmethyl)phenethyl)-4-thiazolyl)benzonitrile 
A triazole with antifungal activity. Ravuconazole inhibits 14a demethylase, an enzyme involved in sterol synthesis, resulting in lysis of the fungal… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
ABSTRACT In this work, we investigated the in vivo activity of ravuconazole against the Y and Berenice-78 Trypanosoma cruzi… Expand
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Highly Cited
2008
Highly Cited
2008
Background Resistance to triazoles was recently reported in Aspergillus fumigatus isolates cultured from patients with invasive… Expand
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Review
2006
Review
2006
Melanins are negatively charged, hydrophobic pigments of high molecular weight ([54][1], [88][2], [95][3], [139][4]) that are… Expand
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Highly Cited
2003
Highly Cited
2003
ABSTRACT We examined the in vitro activity of caspofungin, posaconazole, voriconazole, ravuconazole, itraconazole, and… Expand
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Highly Cited
2003
Highly Cited
2003
Ravuconazole is an experimental triazole derivative with potent and broad-spectrum antifungal activity and a remarkably long half… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT The in vitro activities of ravuconazole and voriconazole were compared with those of amphotericin B, flucytosine (5FC… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Posaconazole, ravuconazole, and voriconazole are new triazole derivatives that possess potent, broad-spectrum antifungal… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Biofilms, likely the predominant mode of device-related microbial infection, exhibit resistance to antimicrobial agents… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT From 1 January 1997 through 31 December 2000, 2,047 bloodstream infections (BSIs) due to Candida spp. were reported from… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT A surveillance program (SENTRY) of bloodstream infections (BSI) in the United States, Canada, Latin America, and Europe… Expand
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