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ravuconazole

Known as: 3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol, p-(2-((alphaR,betaR)-2,4-Difluoro-beta-hydroxy-alpha-methyl-beta-(1H-1,2,4-triazol-1-ylmethyl)phenethyl)-4-thiazolyl)benzonitrile 
A triazole with antifungal activity. Ravuconazole inhibits 14a demethylase, an enzyme involved in sterol synthesis, resulting in lysis of the fungal… 
National Institutes of Health

Papers overview

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Review
2015
Review
2015
Chagas disease, a chronic systemic parasitosis caused by the Kinetoplastid protozoon Trypanosoma cruzi, is the first cause of… 
Highly Cited
2012
Highly Cited
2012
  • F. BucknerJ. Urbina
  • 2012
  • Corpus ID: 27336471
Highly Cited
2006
Highly Cited
2006
ABSTRACT During 2003, a total of 1,397 Candida isolates, 73 Aspergillus isolates, 53 Cryptococcus neoformans isolates, and 25… 
Review
2004
Review
2004
Until the 1940s, relatively few agents were available for the treatment of systemic fungal infections. The development of the… 
Review
2003
Highly Cited
2003
Highly Cited
2003
ABSTRACT In vivo studies have characterized the pharmacodynamic characteristics of the triazole fluconazole. These investigations… 
Highly Cited
2002
Highly Cited
2002
ABSTRACT The in vitro activities of ravuconazole and voriconazole were compared with those of amphotericin B, flucytosine (5FC… 
Highly Cited
2002
Highly Cited
2002
ABSTRACT This collaborative three-center study evaluated NCCLS M38-A document testing conditions and other testing conditions for…