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Epidemiology of Invasive Candidiasis: a Persistent Public Health Problem
Improved non-culture-based diagnostics are needed to expand the potential for preemptive (or early directed) therapy and improve diagnostic, preventive, and therapeutic strategies is necessary to reduce the considerable morbidity and mortality associated with IC. Expand
Methicillin-Resistant Staphylococcus aureus (MRSA) Strain ST398 Is Present in Midwestern U.S. Swine and Swine Workers
Results show that colonization of swine by MRSA was very common on one swine production system in the midwestern U.S., suggesting that agricultural animals could become an important reservoir for this bacterium. Expand
Survey of infections due to Staphylococcus species: frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western
Given the increasing multidrug resistance among staphylococci and the possible emergence of vancomycin-resistant strains, global strategies are needed to control emergence and spread of multiply resistant staphlyococci. Expand
Epidemiology of Invasive Mycoses in North America
The epidemiologic profiles of these invasive mycoses in North America are discussed, as well as risk factors for infection, and the pathogens’ antifungal susceptibility. Expand
Attributable mortality of nosocomial candidemia, revisited.
Nosocomial candidemia is still associated with an extremely high crude and attributable mortality--much higher than that expected from underlying disease alone. Expand
Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: a 10.5-Year Analysis of Susceptibilities of Candida Species to Fluconazole and Voriconazole as Determined by CLSI
This survey identifies several less-common species of Candida with decreased susceptibility to azoles, which may pose a future threat to optimal antifungal therapy and underscore the importance of prompt and accurate species identification and antIFungal susceptibility testing. Expand
Antifungal Susceptibilities of Candida Species Causing Vulvovaginitis and Epidemiology of Recurrent Cases
The results support the use of azoles for empirical therapy of uncomplicated candidal vulvovaginitis and suggest recurrent episodes are more often caused by non-albicans species, for which azole agents are less likely to be effective. Expand
Rare and Emerging Opportunistic Fungal Pathogens: Concern for Resistance beyond Candida albicans and Aspergillus fumigatus
The frequency of invasive mycoses due to opportunistic fungal pathogens has increased significantly over the past two decades (35, 74, 83, 88, 89, 101, 106). This increase in infections is associatedExpand
Evaluation of Current Methods for Detection of Staphylococci with Reduced Susceptibility to Glycopeptides
The direct colony suspension inoculum for this method was found to be equally accurate in detecting (hetero-)glycopeptide-intermediate S. aureus compared to the overnight broth inoculum preparation method. Expand
In Vitro Susceptibility of Invasive Isolates of Candida spp. to Anidulafungin, Caspofungin, and Micafungin: Six Years of Global Surveillance
All three echinocandins have excellent in vitro activities against invasive strains of Candida isolated from centers worldwide and no difference in activity by geographic region is found. Expand