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quinapril

Known as: 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, Quinaprilum, quinapril [Chemical/Ingredient] 
A prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Quinapril is hydrolized into its active… 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (2)

AccuprilCI 906
AngioedemaAngiotensin-Converting Enzyme Inhibitors [MoA]Congestive heart failureDecreased Blood Pressure [PE]

Broader (3)

Angiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsTetrahydroisoquinolines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Ultra-thin-layer chromatography mass spectrometry and thin-layer chromatography mass spectrometry of single peptides of angiotensin-converting enzyme inhibitors.
2010
2010
Serotonin syndrome following Methylene Blue infusion: a rare complication of antidepressant therapy
Methylene Blue (methylthionium chloride, MB) is used in medical practice as an antidote for methaemoglobinaemia, dye, antiseptic… 
2003
2003
Pharmacokinetics of Quinapril in Children: Assessment during Substitution for Chronic Angiotensin‐Converting Enzyme Inhibitor Treatment
Quinapril pharmacokinetics were studied in infants and children using a novel study design that allowed substitution of quinapril… 
2002
2002
Subacute and Chronic Effects of Quinapril on Cardiac Cytokine Expression, Remodeling, and Function After Myocardial Infarction in the Rat
Inflammatory cytokines have been shown to have many cardiotoxic effects and to be activated in patients who have had a myocardial… 
2002
2002
Pretreatment with angiotensin-converting enzyme inhibitors attenuates ischemia-reperfusion injury.
2001
2001
Quinapril treatment enhances vascular sensitivity to insulin
Objective Insulin-mediated vasodilation has been shown to be impaired with hypertension and aggravated by dietary sodium… 
1997
1997
Quinapril decreases renal endothelin-1 expression and synthesis in a normotensive model of immune-complex nephritis.
Angiotensin-converting enzyme (ACE) inhibitors diminish proteinuria and the progression to renal failure in several experimental… 
Highly Cited
1996
Highly Cited
1996
Endothelium-dependent relaxation in resistance arteries from spontaneously hypertensive rats: effect of long-term treatment with perindopril, quinapril, hydralazine or amlodipine
Objective To examine the effects of different types of anti hypertensive treatment on endothelium-dependent relaxation in… 
Review
1992
Review
1992
Circulatory and extracirculatory effects of angiotensin-converting enzyme inhibition.
1990
1990
Digoxin, Converting-Enzyme Inhibition (Quinapril), and the Combination in Patients with Congestive Heart Failure Functional Class II and Sinus Rhythm
Summary: In a randomized single-blind cross-over trial, the efficacy of digoxin, angiotensin-converting enzyme (ACE) inhibition… 
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