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quinapril
Known as:
2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
, Quinaprilum
, quinapril [Chemical/Ingredient]
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A prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Quinapril is hydrolized into its active…
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National Institutes of Health
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Related topics
Related topics
19 relations
Narrower (2)
Accupril
CI 906
Angioedema
Angiotensin-Converting Enzyme Inhibitors [MoA]
Congestive heart failure
Decreased Blood Pressure [PE]
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Broader (3)
Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Agents
Tetrahydroisoquinolines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Ultra-thin-layer chromatography mass spectrometry and thin-layer chromatography mass spectrometry of single peptides of angiotensin-converting enzyme inhibitors.
I. Vovk
,
G. Popović
,
B. Simonovska
,
Alen Albreht
,
D. Agbaba
Journal of Chromatography A
2011
Corpus ID: 22047741
2002
2002
Subacute and Chronic Effects of Quinapril on Cardiac Cytokine Expression, Remodeling, and Function After Myocardial Infarction in the Rat
G. Wei
,
M. Sirois
,
R. Qu
,
P. Liu
,
J. Rouleau
Journal of Cardiovascular Pharmacology
2002
Corpus ID: 27080727
Inflammatory cytokines have been shown to have many cardiotoxic effects and to be activated in patients who have had a myocardial…
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2000
2000
Impairment of Cerebrovascular Reactivity by Methionine-Induced Hyperhomocysteinemia and Amelioration by Quinapril Treatment
C. Chao
,
Yuan-Teh Lee
Stroke
2000
Corpus ID: 1325858
Background and Purpose Human studies have shown that methionine-induced hyperhomocysteinemia impairs brachial artery endothelial…
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1999
1999
Chronic AT1 receptor blockade and angiotensin-converting enzyme (ACE) inhibition in (CHF 146) cardiomyopathic hamsters: effects on cardiac hypertrophy and survival.
N. Bastien
,
Anne-Véronique Juneau
,
Julie Ouellette
,
C. Lambert
Cardiovascular Research
1999
Corpus ID: 14649355
Highly Cited
1997
Highly Cited
1997
Selective Stimulation of Tissue-Type Plasminogen Activator (t-PA) In Vivo by Infusion of Bradykinin
N. Brown
,
J. Nadeau
,
D. Vaughan
Thrombosis and Haemostasis
1997
Corpus ID: 19827816
Summary Angiotensin converting inhibitors (ACEI) not only decrease angiotensin II (Ang II) but also potentiate the effects of…
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Highly Cited
1996
Highly Cited
1996
Endothelium-dependent relaxation in resistance arteries from spontaneously hypertensive rats: effect of long-term treatment with perindopril, quinapril, hydralazine or amlodipine
M. A. Bennett
,
C. Hillier
,
H. Thurston
Journal of Hypertension
1996
Corpus ID: 30516805
Objective To examine the effects of different types of anti hypertensive treatment on endothelium-dependent relaxation in…
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Highly Cited
1995
Highly Cited
1995
Endothelial function in spontaneously hypertensive rats: influence of quinapril treatment
M. Kähönen
,
H. Mäkynen
,
Xiumin Wu
,
P. Arvola
,
I. Pörsti
British Journal of Pharmacology
1995
Corpus ID: 45398306
1 Angiotensin converting enzyme (ACE) inhibition has been shown to restore the impaired endothelial function in hypertension, but…
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Highly Cited
1992
Highly Cited
1992
Effect of timing of administration on the plasma ACE inhibitory activity and the antihypertensive effect of quinapril
P. Palatini
,
A. Racioppa
,
G. Raule
,
M. Zaninotto
,
M. Penzo
,
A. Pessina
Clinical pharmacology and therapy
1992
Corpus ID: 21772835
To assess whether timing of administration can influence the antihypertensive effect of quinapril, 18 patients with hypertension…
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1992
1992
Can an angiotensin-converting enzyme inhibitor with a short half-life effectively lower blood pressure for 24 hours?
P. Palatini
American Heart Journal
1992
Corpus ID: 11301699
Review
1992
Review
1992
Circulatory and extracirculatory effects of angiotensin-converting enzyme inhibition.
M. Weber
,
J. Neutel
,
D. Smith
American Heart Journal
1992
Corpus ID: 37013326
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