Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

quinacillin

Known as: 3-carboxy-2-quinoxalinylpenicillanic acid 
A semisynthetic penicillase-resistant penicillin with antibacterial activity. Quinacillin binds to and inactivates penicillin-binding proteins (PBPs… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1986
1986
Conditions have been established where the deactivation of the beta-lactamase from Staphylococcus aureus PC1 by the penicillin… Expand
1984
1984
The effect of antibody on the reversible deactivation of the beta-lactamase (penicillin amino-beta-lactamhydrolase, EC 3.5.2.6… Expand
Highly Cited
1981
Highly Cited
1981
The characteristics of the reaction of a number of mechanism-based inactivators of the RTEM beta-lactamase have suggested that a… Expand
1978
1978
Abstract Staphylococcal penicillinase (EC 3.5.2.6) is shown to undergo partial, fully reversible inactivation of… Expand
1977
1977
The possibility of a calorimetric determination of the number of homogeneous independent binding sites on the protein molecule… Expand
1975
1975
1. The penicillinase-catalysed hydrolysis of quinacillin was quenched by addition of 5 m-guanidinium chloride or 1% (w/v) sodium… Expand
  • figure 1
  • figure 3
  • figure 2
1966
1966
SUMMARY: It has been shown that when the Gram-positive micro-organisms Bacillus subtilis, Staphylococcus aureus and Streptococcus… Expand
  • table 1
1965
1965
  • G. Ayliffe
  • Journal of general microbiology
  • 1965
  • Corpus ID: 35373412
SUMMARY: Sensitivity to ampicillin and cephalothin, the formation and induction of penicillinase and cephalosporinase, and the… Expand
  • table 2
  • table 3
Highly Cited
1964
Highly Cited
1964
The discovery of penicillinase-resistant penicillins is an important landmark in the history of antibacterial chemotherapy… Expand
1964
1964
QUINACILLIN, the disodium salt of 3-carboxy-2-quinoxalinylpenicillin, has recently been described1,2 and has, for a penicillin… Expand