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quinacillin

Known as: 3-carboxy-2-quinoxalinylpenicillanic acid 
A semisynthetic penicillase-resistant penicillin with antibacterial activity. Quinacillin binds to and inactivates penicillin-binding proteins (PBPs… 
National Institutes of Health

Papers overview

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1986
1986
Conditions have been established where the deactivation of the beta-lactamase from Staphylococcus aureus PC1 by the penicillin… 
Highly Cited
1981
Highly Cited
1981
The characteristics of the reaction of a number of mechanism-based inactivators of the RTEM beta-lactamase have suggested that a… 
1975
1975
1. The penicillinase-catalysed hydrolysis of quinacillin was quenched by addition of 5 m-guanidinium chloride or 1% (w/v) sodium… 
1966
1966
SUMMARY: It has been shown that when the Gram-positive micro-organisms Bacillus subtilis, Staphylococcus aureus and Streptococcus… 
1965
1965
  • G. Ayliffe
  • Journal of general microbiology
  • 1965
  • Corpus ID: 35373412
SUMMARY: Sensitivity to ampicillin and cephalothin, the formation and induction of penicillinase and cephalosporinase, and the… 
Highly Cited
1964
Highly Cited
1964
The discovery of penicillinase-resistant penicillins is an important landmark in the history of antibacterial chemotherapy… 
1964
1964
QUINACILLIN, the disodium salt of 3-carboxy-2-quinoxalinylpenicillin, has recently been described1,2 and has, for a penicillin…