The role of cellular lipid in the resistance of gram-positive bacteria to penicillins.

@article{Hugo1966TheRO,
  title={The role of cellular lipid in the resistance of gram-positive bacteria to penicillins.},
  author={W. B. Hugo and Reginald John Stretton},
  journal={Journal of general microbiology},
  year={1966},
  volume={42 1},
  pages={
          133-8
        }
}
SUMMARY: It has been shown that when the Gram-positive micro-organisms Bacillus subtilis, Staphylococcus aureus and Streptococcus faecalis were grown under conditions in which their cellular lipid was increased a corresponding increase in their resistance to the penicillins benzylpenicillin, cloxacillin, methicillin and quinacillin was produced. Likewise cell-wall lipid depletion caused a corresponding increase in sensitivity. 

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