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pyronaridine

Known as: 4-((7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)amino)-2,6-bis(1-pyrrolidinylmethyl)phenol, 4-((7-chloro-2-methoxybenzo(b)(1,5)naphthyridin-10-yl)amino)-2,6-bis((pyrrolidin-1-yl)methyl)phenol, malaridine 
 
National Institutes of Health

Papers overview

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2012
2012
BACKGROUND Pyronaridine-artesunate is an artemisinin-based combination therapy under evaluation for the treatment of Plasmodium… Expand
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Highly Cited
2011
Highly Cited
2011
Clinical studies and mathematical models predict that, to achieve malaria elimination, combination therapies will need to… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND The development of novel artemisinin-combination therapies suitable for the treatment of pediatric patients suffering… Expand
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2006
2006
Pyronaridine, 2-methoxy-7-chloro-10[3',5'-bis(pyrrolidinyl-1-methyl-)4'hydroxyphenyl]aminobenzyl-(b)-1,5-naphthyridine, a new… Expand
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Highly Cited
1998
Highly Cited
1998
The in-vitro activities of pyronaridine, amodiaquine, chloroquine and quinine were evaluated against 161 isolates of Plasmodium… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND The spread of chloroquine resistance poses a serious problem in Africa, where falciparum malaria transmission is the… Expand
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1996
1996
Pyronaridine, an acridine derivative, has been found effective in China for the treatment of drug-resistant falciparum malaria… Expand
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Highly Cited
1992
Highly Cited
1992
The activities of Mannich base antimalarials, including pyronaridine, have been explored against drug-sensitive (Plasmodium… Expand
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Review
1992
Review
1992
Pyronaridine, a hydroxyanilino-benzonaphthyridine derivative synthesized in 1970, is a new antimalarial compound which has been… Expand
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