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pyronaridine

Known as: 4-((7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)amino)-2,6-bis(1-pyrrolidinylmethyl)phenol, 4-((7-chloro-2-methoxybenzo(b)(1,5)naphthyridin-10-yl)amino)-2,6-bis((pyrrolidin-1-yl)methyl)phenol, malaridine 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

AntimalarialsNaphthyridines

Narrower (2)

benzonaphthyridine 7351pyronaridine phosphate salt

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Combination therapies for malaria are failing--what next?
2011
2011
Baseline In Vitro Activities of the Antimalarials Pyronaridine and Methylene Blue against Plasmodium falciparum Isolates from Kenya
ABSTRACT We have analyzed the in vitro activities of pyronaridine and methylene blue against 59 Plasmodium falciparum isolates… 
2006
2006
Determination of the physicochemical properties of pyronaridine - a new antimalarial drug.
The physicochemical properties of pyronaridine, a new antimalarial drug, have been determined for the first time in this study… 
Highly Cited
1998
Highly Cited
1998
Efficacy of oral pyronaridine for the treatment of acute uncomplicated falciparum malaria in African children.
Pyronaridine is a new antimalarial agent developed in China. In this randomized, unblinded study, the safety, tolerance, and… 
1997
1997
The chemotherapy of rodent malaria. LV. Interactions between pyronaridine and artemisinin.
Two interactions of two potent blood schizontocides, pyronaridine and artemisinin, were assessed in mice infected with… 
1996
1996
The effects of pyronaridine on the morphology of Plasmodium falciparum in Aotus trivirgatus.
The effects of pyronaridine on the morphology of Plasmodium falciparum were studied in an infected owl monkey (Aotus trivirgatus… 
1994
1994
In vitro susceptibility of Cambodian isolates of Plasmodium falciparum to halofantrine, pyronaridine and artemisinin derivatives.
Multidrug-resistant Plasmodium falciparum is widespread in Cambodia. The in vitro susceptibilities of 14 Cambodian isolates to… 
1991
1991
A 5-year surveillance of sensitivity in vivo of Plasmodium falciparum to pyronaridine/sulfadoxine/pyrimethamine in Diaoluo area, Hainan Province.
The surveillance of sensitivity of P. falciparum to pyronaridine/sulfadoxine/pyrimethamine has been carried out in Diaoluo area… 
1991
1991
Pyronaridine: A new antimalarial drug.
1982
1982
[Synthesis of new antimalarial drug pyronaridine and its analogues (author's transl)].
On the basis of structure-activity relationship of some antimalarial drugs, the authors synthesized a new compound 2-methoxy-7… 
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