pyronaridine

Known as: 4-((7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)amino)-2,6-bis(1-pyrrolidinylmethyl)phenol, 4-((7-chloro-2-methoxybenzo(b)(1,5)naphthyridin-10-yl)amino)-2,6-bis((pyrrolidin-1-yl)methyl)phenol, malaridine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2018
051019822018

Papers overview

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2012
2012
BACKGROUND Pyronaridine-artesunate is an artemisinin-based combination therapy under evaluation for the treatment of Plasmodium… (More)
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2008
2008
BACKGROUND The development of novel artemisinin-combination therapies suitable for the treatment of pediatric patients suffering… (More)
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2008
2008
Pyronaridine is a Mannich base anti-malarial with demonstrated efficacy against drug resistant Plasmodium falciparum, P. vivax, P… (More)
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2006
2006
Pyronaridine, 2-methoxy-7-chloro-10[3',5'-bis(pyrrolidinyl-1-methyl-)4'hydroxyphenyl]aminobenzyl-(b)-1,5-naphthyridine, a new… (More)
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1998
1998
Life-threatening agranulocytosis and hepatotoxicity during prophylactic administration of amodiaquine have led to its withdrawal… (More)
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1998
1998
The in-vitro activities of pyronaridine, amodiaquine, chloroquine and quinine were evaluated against 161 isolates of Plasmodium… (More)
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1996
1996
Pyronaridine, an acridine derivative, has been found effective in China for the treatment of drug-resistant falciparum malaria… (More)
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1996
1996
BACKGROUND The spread of chloroquine resistance poses a serious problem in Africa, where falciparum malaria transmission is the… (More)
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1992
1992
The activities of Mannich base antimalarials, including pyronaridine, have been explored against drug-sensitive (Plasmodium… (More)
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1991
1991
The worldwide spread of strains of Plasmodium falciparum that are resistant to chloroquine has highlighted the urgent need for… (More)
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