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Long-QT syndrome is a clinically and genetically heterogeneous syndrome characterized by lengthening of the QT interval and… Expand Voltage-dependent modification of Vmax (the maximum upstroke velocity of the action potential) recovery from use-dependent block… Expand The interactions of the class I antiarrhythmic agents, disopyramide, pirmenol, and pentisomide with peripheral muscarinic… Expand 1. The effect of the local anaesthetic penticainide (2‐alkyl‐(4‐dialkylamino)‐2‐pyridyl‐butyramide) on macroscopic and single… Expand Effects of new antiarrhythmic drugs, pentisomide [3.5 ± 0.5 mg/kg intravenously (i.v.) n = 8], and E-4031 (5.6 ± 1.0 μg/kg, n = 8… Expand 1. The blocking mechanism of a disopyramide derivative Penticainide (2‐alkyl‐(4‐(dialkylamino)‐2‐)pyridyl‐butyramide) on cardiac… Expand The intracellular electrophysiological properties of a new antiarrhythmic agent, penticainide (5 X 10-6 to 5 X 10-5 M) were… Expand The electrophysiological effects of three class I antiarrhythmic drugs, lignocaine, disopyramide, and penticainide, were compared… Expand The blocking mechanism of the Na+ channel by penticainide, a disopyramide analogue, was studied in rabbit cardiac Purkinje fibers… Expand The antiarrhythmic efficacy of a new class I agent, penticainide, was evaluated by acute oral drug testing and compared in the… Expand