Skip to search formSkip to main contentSkip to account menu

propisomide

Known as: 2-(2-(diisopropylamino)ethyl)-4-methyl-2-(2-pyridyl)pentamide, PENTISOMIDE, penticainide 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (4)

Anti-Arrhythmia AgentsLocal AnestheticsPropylaminesPyridines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1992
1992
Selectivity of class I antiarrhythmic agents, disopyramide, pirmenol, and pentisomide for peripheral muscarinic M2 and M3 receptors.
The interactions of the class I antiarrhythmic agents, disopyramide, pirmenol, and pentisomide with peripheral muscarinic… 
1992
1992
Voltage‐Dependent Modification of Vmax Recovery from Use‐Dependent Block by Pirmenol in Guinea Pig Papillary Muscles: Comparison with Other Class I Drugs
Voltage-dependent modification of Vmax (the maximum upstroke velocity of the action potential) recovery from use-dependent block… 
1991
1991
Dual effect of the local anaesthetic penticainide on the Na+ current of guinea‐pig ventricular myocytes.
1. The effect of the local anaesthetic penticainide (2‐alkyl‐(4‐dialkylamino)‐2‐pyridyl‐butyramide) on macroscopic and single… 
1991
1991
Effects of Pentisomide and E‐4031 on Canine Atrial Flutter Due to Reentry: A Comparative Study with Disopyramide and Propafenone
Effects of new antiarrhythmic drugs, pentisomide [3.5 ± 0.5 mg/kg intravenously (i.v.) n = 8], and E-4031 (5.6 ± 1.0 μg/kg, n = 8… 
1991
1991
Effect of Pentisomide (CM 7857) on Myocardial Excitation, Conduction, Repolarization, and Refractoriness. An Electrophysiological Study in Humans
The electrophysiological effects of pentisomide upon the intact human heart were evaluated using programmed stimulationand… 
1989
1989
Properties of the block of single Na+ channels in guinea‐pig ventricular myocytes by the local anaesthetic penticainide.
1. The blocking mechanism of a disopyramide derivative Penticainide (2‐alkyl‐(4‐(dialkylamino)‐2‐)pyridyl‐butyramide) on cardiac… 
1989
1989
Electrophysiological Effects of Penticainide (CM 7857) in Isolated Human Atrial and Ventricular Fibers
The intracellular electrophysiological properties of a new antiarrhythmic agent, penticainide (5 X 10-6 to 5 X 10-5 M) were… 
1988
1988
Hemodynamic Effects of Penticainide (CM 7857), a Novel Class I Antiarrhythmic Drug–Comparison with Disopyramide
Penticainide (CM 7857) is a new class I antiarrhythmic agent, which has been shown to suppress ventricular arrhythmias by a… 
1987
1987
Electrophysiological Studies of Penticainide (CM 7857), a New Antiarrhythmic Agent, in Mammalian Myocardium
The intracellular electrophysiologic properties of a new antiarrhythmic substance, penticainide, were studied in isolated rabbit… 
1987
1987
HPLC measurement of penticainide and desalkylpenticainide in biological fluids.
A simple HPLC method has been developed to measure the antiarrhythmic agent penticainide and its N-desalkyl metabolite in… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)