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propisomide

Known as: 2-(2-(diisopropylamino)ethyl)-4-methyl-2-(2-pyridyl)pentamide, PENTISOMIDE, penticainide 
National Institutes of Health

Related topics

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4 relations

Broader (4)

Anti-Arrhythmia AgentsLocal AnestheticsPropylaminesPyridines

Papers overview

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1992
1992
Selectivity of class I antiarrhythmic agents, disopyramide, pirmenol, and pentisomide for peripheral muscarinic M2 and M3 receptors.
The interactions of the class I antiarrhythmic agents, disopyramide, pirmenol, and pentisomide with peripheral muscarinic… 
1992
1992
Voltage‐Dependent Modification of Vmax Recovery from Use‐Dependent Block by Pirmenol in Guinea Pig Papillary Muscles: Comparison with Other Class I Drugs
Voltage-dependent modification of Vmax (the maximum upstroke velocity of the action potential) recovery from use-dependent block… 
1991
1991
Dual effect of the local anaesthetic penticainide on the Na+ current of guinea‐pig ventricular myocytes.
1. The effect of the local anaesthetic penticainide (2‐alkyl‐(4‐dialkylamino)‐2‐pyridyl‐butyramide) on macroscopic and single… 
1991
1991
Effects of Pentisomide and E‐4031 on Canine Atrial Flutter Due to Reentry: A Comparative Study with Disopyramide and Propafenone
Effects of new antiarrhythmic drugs, pentisomide [3.5 ± 0.5 mg/kg intravenously (i.v.) n = 8], and E-4031 (5.6 ± 1.0 μg/kg, n = 8… 
1989
1989
Properties of the block of single Na+ channels in guinea‐pig ventricular myocytes by the local anaesthetic penticainide.
1. The blocking mechanism of a disopyramide derivative Penticainide (2‐alkyl‐(4‐(dialkylamino)‐2‐)pyridyl‐butyramide) on cardiac… 
1989
1989
Electrophysiological Effects of Penticainide (CM 7857) in Isolated Human Atrial and Ventricular Fibers
The intracellular electrophysiological properties of a new antiarrhythmic agent, penticainide (5 X 10-6 to 5 X 10-5 M) were… 
1988
1988
Comparative effects of three class I antiarrhythmic drugs on plateau and pacemaker currents of sheep cardiac Purkinje fibres.
The electrophysiological effects of three class I antiarrhythmic drugs, lignocaine, disopyramide, and penticainide, were compared… 
1988
1988
Activation block and trapping of penticainide, a disopyramide analogue, in the Na+ channel of rabbit cardiac Purkinje fibers.
The blocking mechanism of the Na+ channel by penticainide, a disopyramide analogue, was studied in rabbit cardiac Purkinje fibers… 
1987
1987
Electrophysiological Studies of Penticainide (CM 7857), a New Antiarrhythmic Agent, in Mammalian Myocardium
The intracellular electrophysiologic properties of a new antiarrhythmic substance, penticainide, were studied in isolated rabbit… 
1985
1985
Protein binding of propisomide.
This paper describes the protein binding of propisomide to human serum and isolated proteins using equilibrium dialysis. The drug… 
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