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proline, 2-oxoglutarate 3-dioxygenase

Known as: proline 3-hydroxylase, prolyl 3-hydroxylase 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
012319772017

Related topics

Related topics

1 relation

Broader (1)

Procollagen-Proline Dioxygenase

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
proline, 2-oxoglutarate 3-dioxygenase
Procollagen-Proline Dioxygenase

Papers overview

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2013
2013
Posttranslational modifications in type I collagen from different tissues extracted from wild type and prolyl 3-hydroxylase 1 null mice.
Type I collagen extracted from tendon, skin, and bone of wild type and prolyl 3-hydroxylase 1 (P3H1) null mice shows distinct… (More)
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Highly Cited
2010
Highly Cited
2010
Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding.
Osteogenesis imperfecta is a heritable disorder that causes bone fragility. Mutations in type I collagen result in autosomal… (More)
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2010
2010
Prolyl 3-hydroxylase 1 and CRTAP are mutually stabilizing in the endoplasmic reticulum collagen prolyl 3-hydroxylation complex.
Null mutations in cartilage-associated protein (CRTAP) and prolyl 3-hydroxylase 1 (P3H1/LEPRE1) cause types VII and VIII OI… (More)
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2010
2010
Prolyl 3-hydroxylase 1 null mice display abnormalities in fibrillar collagen-rich tissues such as tendons, skin, and bones.
Osteogenesis imperfecta (OI) is a skeletal disorder primarily caused by mutations in the type I collagen genes. However, recent… (More)
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2009
2009
Biochemical characterization of the prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B complex.
The rough endoplasmic reticulum-resident protein complex consisting of prolyl 3-hydroxylase 1 (P3H1), cartilage-associated… (More)
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2009
2009
Expression of prolyl 3-hydroxylase genes in embryonic and adult mouse tissues.
Collagen requires hydroxylation of its proline residues to achieve proper assembly, structure, and function. Prolyl 4-hydroxylase… (More)
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2008
2008
Characterization of recombinant human prolyl 3-hydroxylase isoenzyme 2, an enzyme modifying the basement membrane collagen IV.
The single 3-hydroxyproline residue in the collagen I polypeptides is essential for proper fibril formation and bone development… (More)
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Highly Cited
2004
Highly Cited
2004
Prolyl 3-hydroxylase 1, enzyme characterization and identification of a novel family of enzymes.
The collagen prolyl hydroxylases are enzymes that are required for proper collagen biosynthesis, folding, and assembly. They… (More)
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2001
2001
Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases.
Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyse oxidative reactions in a range of metabolic processes including the… (More)
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1997
1997
Purification and cloning of a proline 3-hydroxylase, a novel enzyme which hydroxylates free L-proline to cis-3-hydroxy-L-proline.
Proline 3-hydroxylase was purified from Streptomyces sp. strain TH1, and its structural gene was cloned. The purified enzyme… (More)
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