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Procollagen-Proline Dioxygenase

Known as: Peptidyl Proline Hydroxylase, Prolyl 4-Hydroxylase, Procollagen, Protocollagen Proline 4-Hydroxylase 
A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl containing peptide, usually in PROTOCOLLAGEN, to a hydroxyprolylglycyl… 
National Institutes of Health

Related topics

Related topics

20 relations
In BloodP4HA1 geneP4HA2 geneP4HB gene

Broader (1)

Mixed Function Oxygenases

Narrower (5)

P4HA1 protein, humanP4hb protein, mouseP4hb protein, ratPHD2 protein, rat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1995
Highly Cited
1995
Purification and characterization of toluene 2-monooxygenase from Burkholderia cepacia G4.
Recent in vivo studies indicate that ring monooxygenation is a widespread mechanism by which bacteria metabolize aromatic… 
Highly Cited
1986
Highly Cited
1986
Delineation of a Particulate Thyrotropin‐Releasing Hormone‐Degrading Enzyme in Rat Brain by the Use of Specific Inhibitors of Prolyl Endopeptidase and Pyroglutamyl Peptide Hydrolase
Abstract: The degradation of thyrotropin‐releasing hormone in rat brain homogenates was studied in the presence of N… 
Highly Cited
1982
Highly Cited
1982
CHEMOSENSITIVITY OF WALKING LEGS OF THE LOBSTER HOMARUS AMERICANUS: NEUROPHYSIOLOGICAL RESPONSE SPECTRUM AND THRESHOLDS
SUMMARY Responses of chemoreceptors in the walking legs of the lobster Homarus americanus to 35 individual compounds and 3… 
Review
1978
Review
1978
Inhibition of prolactin secretion by histidyl-proline-diketopiperazine
ON the basis of its activity as a thyrotropin-releasing factor, the tripeptide pyroGlu-His-Pro-NH2 (TRH) has been isolated from… 
Highly Cited
1977
Highly Cited
1977
FAMILIAL HEMOCHROMATOSIS: CHARACTERISTICS OF THE PRE‐CIRRHOTIC STAGE IN A LARGE KINDRED
Ffty asymptomatic members of a kindred with familial hemochromatosis were studied in an effort to clarify some of the physiologic… 
Highly Cited
1975
Highly Cited
1975
An affinity-column procedure using poly(L-proline) for the purification of prolyl hydroxylase. Purification of the enzyme from chick embryos.
An affinity column procedure is reported for purifying prolyl hydroxylase. The procedure is based on the affinity of the enzyme… 
Highly Cited
1973
Highly Cited
1973
Collagen Synthesis: Localization of Prolyl Hydroxylase in Tendon Cells Detected with Ferritin-Labeled Antibodies
An improved procedure was employed for linking ferritin to antibodies against prolyl hydroxylase, the enzyme that synthesizes the… 
Highly Cited
1971
Highly Cited
1971
Intestinal transport of amino acid residues of dipeptides. I. Influx of the glycine residue of glycyl-L-proline across mucosal border.
Highly Cited
1969
Highly Cited
1969
Polymers of tripeptides as collagen models. IV. Structure analysis of poly(L-proly-glycyl-L-proline).
Highly Cited
1962
Highly Cited
1962
Conversion of proline U-C14 to labeled hydroxyproline by rat cartilage in vitro: effects of hypophysectomy, growth hormone, and cortisol.
Abstract Endocrine effects on collagen synthesis have been studied by measuring the incorporation of proline into Hydroxyproline… 
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