profilin 1

Known as: Profilin I, Profilin-1 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Cells contain multiple F-actin assembly pathways, including the Arp2/3 complex, formins, and Ena/VASP, which have largely been… (More)
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2014
2014
The tumour vascular microenvironment supports tumorigenesis not only by supplying oxygen and diffusible nutrients but also by… (More)
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Highly Cited
2012
Highly Cited
2012
Dynamic actin cytoskeletal reorganization is integral to cell motility. Profilins are well-characterized regulators of actin… (More)
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2012
2012
Angiogenesis, the formation of new blood vessels, is fundamental to development and post-injury tissue repair. Vascular… (More)
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2012
2012
Profilin-1 (PFN1) plays an important role in the control of actin dynamics, and could represent an important therapeutic target… (More)
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Highly Cited
2009
Highly Cited
2009
We previously showed that silencing profilin-1 (Pfn1) expression increases breast cancer cell motility, but the underlying… (More)
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Highly Cited
2007
Highly Cited
2007
Expression of profilin-1 (Pfn1) is downregulated in breast cancer cells, the functional significance of which is yet to be… (More)
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2007
2007
Atherosclerosis-related events are a major cause of morbidity and death worldwide, but the mechanisms underlying atherogenesis… (More)
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Highly Cited
2006
Highly Cited
2006
Expression of several actin-binding proteins including profilin-1 is up-regulated during capillary morphogenesis of endothelial… (More)
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1993
1993
We have isolated a 1.7 kbp cDNA encoding a 140 amino acid protein (15.1 kDa, pI 5.91) with a high sequence similarity (62%) to… (More)
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