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profilin 1

Known as: Profilin I, Profilin-1 
National Institutes of Health

Related topics

Related topics

3 relations
PFN1 gene

Narrower (1)

PFN1 protein, human

Broader (1)

Profilins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Role of GSPE in improving early cerebral vascular damage by inhibition of Profilin-1 expression in a ouabain-induced hypertension model.
OBJECTIVE Grape seed proanthocyanidin extract (GSPE), as one of the most popular natural drug extracted from the grape, has been… 
2017
2017
Self-Assembly of Human Profilin-1 Detected by Carr-Purcell-Meiboom-Gill Nuclear Magnetic Resonance (CPMG NMR) Spectroscopy.
Protein oligomerization in the cell has important implications for both health and disease, and an understanding of the… 
2017
2017
Downregulation of Profilin-1 Expression Attenuates Cardiomyocytes Hypertrophy and Apoptosis Induced by Advanced Glycation End Products in H9c2 Cells
Cardiomyocytes hypertrophy and apoptosis induced by advanced glycation end products (AGEs) is the crucial pathological foundation… 
2017
2017
Profilin-1 contributes to cardiac injury induced by advanced glycation end-products in rats
Cardiac injury, including hypertrophy and fibrosis, induced by advanced glycation end products (AGEs) has an important function… 
2015
2015
Subcellular Localization and Ser-137 Phosphorylation Regulate Tumor-suppressive Activity of Profilin-1*
Background: The actin-binding protein profilin-1 is a eukaryotic protein essential for growth, with poorly understood antitumor… 
Review
2014
Review
2014
The multifaceted role of profilin-1 in adipose tissue inflammation and glucose homeostasis
Profilin-1 (pfn) is a small ubiquitous protein that can bind to: (1) G-actin, (2) phosphatidylinositol 4,5-bisphosphate, and (3… 
2014
2014
A High-Content, Multiplexed Screen in Human Breast Cancer Cells Identifies Profilin-1 Inducers with Anti-Migratory Activities
Profilin-1 (Pfn-1) is a ubiquitously expressed actin-binding protein that is essential for normal cell proliferation and… 
2012
2012
Vascular Remodeling–Associated Hypertension Leads to Left Ventricular Hypertrophy and Contractile Dysfunction in Profilin-1 Transgenic Mice
Abstract: Hypertension is a major health problem and a main risk factor for cardiovascular diseases. We have shown that… 
2012
2012
Carotenoid exposure of Caco-2 intestinal epithelial cells did not affect selected inflammatory markers but altered their proteomic response.
Carotenoid consumption has been linked to a number of beneficial health effects, including the reduction of chronic diseases such… 
2009
2009
In birds, profilin-2a is ubiquitously expressed and contributes to actin-based motility
Profilins are small actin-binding proteins expressed in all eukaryotes. They are involved in the regulation of actin filament… 
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