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pridopidine

Known as: 4-(3-(methylsulfonyl)phenyl)-1-propylpiperidine, huntexil, 4-(3-methanesulfonylphenyl)-1-propylpiperidine 
 
National Institutes of Health

Papers overview

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2019
2019
BACKGROUND Previous trials have shown that pridopidine might reduce motor impairment in patients with Huntington's disease. The… Expand
2019
2019
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease affecting both the upper and lower motor neurons (MNs… Expand
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Highly Cited
2017
Highly Cited
2017
The tri-nucleotide repeat expansion underlying Huntington disease (HD) results in corticostriatal synaptic dysfunction and… Expand
2016
2016
Pridopidine has demonstrated improvement in Huntington Disease (HD) motor symptoms as measured by secondary endpoints in clinical… Expand
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2015
2015
RationaleDopamine stabilizers have stimulatory actions under low dopamine tone and inhibitory actions under high dopamine tone… Expand
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2015
2015
Huntington disease (HD) is a neurodegenerative disorder for which new treatments are urgently needed. Pridopidine is a new… Expand
Highly Cited
2013
Highly Cited
2013
We examined the effects of 3 dosages of pridopidine, a dopamine‐stabilizing compound, on motor function and other features of… Expand
Highly Cited
2011
Highly Cited
2011
BACKGROUND Huntington's disease is a progressive neurodegenerative disorder, characterised by motor, cognitive, and behavioural… Expand
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Highly Cited
2010
Highly Cited
2010
Objectives:To evaluate the efficacy and safety of the dopaminergic stabilizer pridopidine (ACR16) in patients with Huntington's… Expand
Highly Cited
2006
Highly Cited
2006
“Dopamine stabilizers” are a new class of compounds that have the ability to reverse both hypo- as well as hyperdopaminergia in… Expand
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