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pridopidine

Known as: 4-(3-(methylsulfonyl)phenyl)-1-propylpiperidine, huntexil, 4-(3-methanesulfonylphenyl)-1-propylpiperidine 
 
National Institutes of Health

Papers overview

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2017
2017
The tri-nucleotide repeat expansion underlying Huntington disease (HD) results in corticostriatal synaptic dysfunction and… Expand
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2017
2017
Pridopidine is currently under clinical development for Huntington disease (HD), with on-going studies to better characterize its… Expand
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2016
2016
Pridopidine has demonstrated improvement in Huntington Disease (HD) motor symptoms as measured by secondary endpoints in clinical… Expand
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2015
2015
RationaleDopamine stabilizers have stimulatory actions under low dopamine tone and inhibitory actions under high dopamine tone… Expand
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2015
2015
Huntington disease (HD) is a neurodegenerative disorder for which new treatments are urgently needed. Pridopidine is a new… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Huntington's disease is a progressive neurodegenerative disorder, characterised by motor, cognitive, and behavioural… Expand
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2010
2010
OBJECTIVES To evaluate the efficacy and safety of the dopaminergic stabilizer pridopidine (ACR16) in patients with Huntington's… Expand
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2010
2010
A new pharmacological class of CNS ligands with the unique ability to stimulate or suppress motor and behavioral symptoms… Expand
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2010
2010
Modification of the partial dopamine type 2 receptor (D(2)) agonist 3-(1-benzylpiperidin-4-yl)phenol (9a) generated a series of… Expand
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2006
2006
"Dopamine stabilizers" are a new class of compounds that have the ability to reverse both hypo- as well as hyperdopaminergia in… Expand
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