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pridopidine

Known as: 4-(3-(methylsulfonyl)phenyl)-1-propylpiperidine, huntexil, 4-(3-methanesulfonylphenyl)-1-propylpiperidine 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Sigma-1 receptor (S1R) is a multi-functional, ligand-operated protein situated in endoplasmic reticulum (ER) membranes and… 
Highly Cited
2019
Highly Cited
2019
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease affecting both the upper and lower motor neurons (MNs… 
2018
2018
Pridopidine is a small molecule in clinical development for the treatment of Huntington’s disease. It was recently found to have… 
Review
2017
Review
2017
Current measures of neurodegenerative diseases are highly subjective and based on episodic visits. Consequently, drug development… 
2017
2017
Pridopidine is currently under clinical development for Huntington disease (HD), with on-going studies to better characterize its… 
Highly Cited
2016
Highly Cited
2016
Pridopidine has demonstrated improvement in Huntington Disease (HD) motor symptoms as measured by secondary endpoints in clinical… 
2015
2015
RationaleDopamine stabilizers have stimulatory actions under low dopamine tone and inhibitory actions under high dopamine tone… 
Highly Cited
2013
Highly Cited
2013
We examined the effects of 3 dosages of pridopidine, a dopamine‐stabilizing compound, on motor function and other features of… 
Highly Cited
2006
Highly Cited
2006
“Dopamine stabilizers” are a new class of compounds that have the ability to reverse both hypo- as well as hyperdopaminergia in…