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premafloxacin

Known as: 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((3R)-3-((1S)-1-(methylamino)ethyl)-1-pyrrolidinyl)-4-oxo-3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-{3-[1-(methylamino)ethyl]-1-pyrrolidinyl}-4-oxo-3-quinolinecarboxylic acid 
National Institutes of Health

Papers overview

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2006
2006
A chiral ligand-controlled conjugate addition reaction of lithium benzyl(trimethylsilyl)amide with tert-butyl enoates gave the… 
2004
2004
ABSTRACT Seventeen qnr-containing transconjugants were constructed with azide-resistant Escherichia coli J53 as the recipient… 
Highly Cited
2003
Highly Cited
2003
ABSTRACT We report for the first time low-level quinolone resistance mediated by decreased expression of topoisomerase IV in… 
2003
2003
N-Methyl-N-[(1S)-1-[(3R)-pyrrolidin-3-yl]ethyl]amine (1)(1) is a key intermediate in the preparation of premafloxacin (2), which… 
Highly Cited
2001
Highly Cited
2001
  • C. Gu, D. Grant
  • Journal of pharmaceutical sciences
  • 2001
  • Corpus ID: 41269764
The transition temperature, T(t), of polymorphs is estimated from both their heats of solution and solubilities (or intrinsic… 
Highly Cited
2000
Highly Cited
2000
Minimum inhibitory concentrations were determined for 811 strains of Staphylococcus aureus isolated from cases of bovine mastitis… 
Highly Cited
2000
Highly Cited
2000
ABSTRACT Premafloxacin is a novel 8-methoxy fluoroquinolone with enhanced activity against Staphylococcus aureus. We found… 
1997
1997
The in vitro activity of premafloxacin against 673 veterinary pathogens was evaluated. Premafloxacin was equivalent to… 
1997
1997
The quinolone antibiotic premafloxacin crystallizes in at least five solid modifications, including three anhydrous phases (Forms… 
1996
1996
The present multicenter study proposes broth microdilution quality control (QC) ranges for the antimicrobial agents ceftiofur…