potassium oxonate

Known as: Oxonic Acid, Potassium Salt, Oteracil Potassium, Oxo 
The potassium salt of oxonate, an enzyme inhibitor that modulates 5- fluorouracil (5-FU) toxicity. Potassium oxonate inhibits orotate… (More)

Topic mentions per year

Topic mentions per year

1965-2017
020406019652017

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND The best chemotherapy regimen for metastatic gastric cancer is uncertain, but promising findings have been reported… (More)
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Highly Cited
2006
Highly Cited
2006
Extensive evidence from contextual fear conditioning experiments suggests that the hippocampus is involved in processing memory… (More)
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Highly Cited
2003
Highly Cited
2003
In cortisone reductase deficiency (CRD), activation of cortisone to cortisol does not occur, resulting in adrenocorticotropin… (More)
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Highly Cited
2003
Highly Cited
2003
Oxalate oxidase (OXO) converts oxalic acid (OA) and O(2) to CO(2) and hydrogen peroxide (H(2)O(2)), and acts as a source of H(2)O… (More)
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Highly Cited
2000
Highly Cited
2000
Channels from KCNQ2 and KCNQ3 genes have been suggested to underlie the neuronal M-type K(+) current. The M current is modulated… (More)
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Highly Cited
2000
Highly Cited
2000
1. KCNQ1-4 potassium channels were expressed in mammalian Chinese hamster ovary (CHO) cells stably transfected with M1 muscarinic… (More)
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Highly Cited
1999
Highly Cited
1999
S-1 is a novel oral fluorouracil antitumor drug that combines three pharmacological agents: tegafur (FT), which is a prodrug of 5… (More)
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Highly Cited
1998
Highly Cited
1998
S-1 is a novel oral anticancer drug, composed of tegafur (FT), gimestat (CDHP) and otastat potassium (Oxo) in a molar ratio of 1… (More)
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Highly Cited
1996
Highly Cited
1996
The purpose of this study was to establish a nude rat orthotopic (organ-specific) human colorectal cancer model as an in vivo… (More)
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Highly Cited
1996
Highly Cited
1996
We have focused our attention on the development of a novel form of a tegafur-based [FT; a prodrug of 5-fluorouracil (5-FU… (More)
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