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Oxonic Acid

Known as: Oteracil, Allantoxanic acid, Oxonic Acid [Chemical/Ingredient] 
A modulator of 5-fluorouracil (5-FU) activity and inhibitor of the enzyme orotate phosphoribosyl-transferase (OPRT), with chemoprotective activity… 
National Institutes of Health

Related topics

Related topics

11 relations
In BloodOxonateagonistsanalogs & derivatives

Narrower (3)

S-1 Antimetabolite agentallantoxanamidepotassium oxonate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
A New Era of Systemic Therapy for Hepatocellular Carcinoma with Regorafenib and Lenvatinib
The SHARP study in 2007 [1] and the Asia Pacific study in 2008 [2] led to the worldwide approval of sorafenib as the standard… 
2015
2015
Phase II clinical trial of metronomic chemotherapy with combined irinotecan and tegafur–gimeracil–oteracil potassium in metastatic and recurrent breast cancer
BackgroundWe investigated the efficacy and safety of metronomic chemotherapy with combined irinotecan and tegafur–gimeracil… 
Review
2015
Review
2015
Long-Term Survival Following Pancreatectomy and S-1 Chemotherapy for Pancreatic Acinar Cell Carcinoma With Peritoneal Dissemination
AbstractCurrent case is the third report of S-1 chemotherapy against acinar cell carcinoma (ACC) of pancreas, and our patient has… 
2014
2014
Adaptation of international guidelines for metastatic colorectal cancer: an asian consensus.
2012
2012
Primary percutaneous coronary intervention and intravascular ultrasound imaging for coronary thrombosis after cisplatin-based chemotherapy
Although cisplatin is indispensable for the chemotherapy treatment of many malignancies, cisplatin-associated thrombosis is… 
2010
2010
Feasibility study of postoperative adjuvant chemotherapy with S-1 (tegaful, gimeracil, oteracil potassium) for non-small cell lung cancer-LOGIK 0601 study.
Review
2006
Review
2006
Chemotherapy sensitivity and resistance testing: to be “standard” or to be individualized, that is the question
Radical surgery with extended lymph-node dissection is the treatment of first choice and the only curative treatment for locally… 
1977
1977
Effect of increased serum urate levels on virgin rats with no arteriosclerosis versus breeder rats with preexistent arteriosclerosis.
1972
1972
Metabolic transformations of 5-azauracil and 5-azaorotic acid in mouse liver and Escherichia coli. Effect on the synthesis of pyrimidines.
1967
1967
Studies on the control of pyrimidine biosynthesis in human diploid cell strains. II. Effects of 5-azaorotic acid, barbituric acid, and pyrimidine precursors on cellular phenotype.
Human diploi(l cell strains grown in 6-azauridine (6-AZUR) acquire increased activity for orotidine-.5v'-monophosphate (OM\[P… 
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