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polycefin

 
National Institutes of Health

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Papers overview

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2013
2013
Abstract A50: Nanobiocojugates of differential imaging and treatment of brain metastatic tumors
Introduction: A significant clinical problem with brain metastatic (BM) tumors is drug delivery and diagnostic imaging to verify… Expand
2013
2013
Nanobioconjugates for Differential Imaging of Solid and Metastatic Brain Tumors
SUMMARY Dynamic contrast enhancement is shown to allow differential MRI detection of human primary brain and metastatic breast… Expand
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2013
2013
Abstract 3911: Imaging and treatment of brain metastatic tumors using nanopolymers.
A significant clinical problem with brain metastatic (BM) tumors is drug delivery and diagnostic imaging to verify MRI… Expand
Highly Cited
2012
Highly Cited
2012
Cellular Delivery of Doxorubicin via pH-Controlled Hydrazone Linkage Using Multifunctional Nano Vehicle Based on Poly(β-L-Malic Acid)
Doxorubicin (DOX) is currently used in cancer chemotherapy to treat many tumors and shows improved delivery, reduced toxicity and… Expand
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2010
2010
Abstract 3854: Newly designed nanobioconjugate for direct targeting and systemic treatment of HER2-positive breast cancer
Objective: We have developed an efficient nanobipolymer drug delivery system Polycefin based on natural-derived biodegradable… Expand
2009
2009
Direct tumor targeting using nanobioconjugate with a combination of monoclonal antibodies for breast cancer treatment.
CTRC-AACR San Antonio Breast Cancer Symposium: 2008 Abstracts Abstract #2124 Objective: Nanobioconjugate engineered based on… Expand
Highly Cited
2008
Highly Cited
2008
Nanoconjugate based on polymalic acid for tumor targeting.
A new prototype of polymer-derived drug delivery system, the nanoconjugate Polycefin, was tested for its ability to accumulate in… Expand
Review
2008
Review
2008
Poly(malic acid) nanoconjugates containing various antibodies and oligonucleotides for multitargeting drug delivery.
Nanoconjugates are emerging as promising drug-delivery vehicles because of their multimodular structure enabling them to actively… Expand
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Highly Cited
2006
Highly Cited
2006
Polycefin, a new prototype of a multifunctional nanoconjugate based on poly(beta-L-malic acid) for drug delivery.
A new prototype of nanoconjugate, Polycefin, was synthesized for targeted delivery of antisense oligonucleotides and monoclonal… Expand
Highly Cited
2006
Highly Cited
2006
Inhibition of laminin-8 in vivo using a novel poly(malic acid)-based carrier reduces glioma angiogenesis
We have previously shown that laminin-8, a vascular basement membrane component, was overexpressed in human glioblastomas… Expand
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