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pluramycin

Known as: 10-(4-O-acetyl-2,3,6-trideoxy-3-(dimethylamino)- 3-C-methyl-alpha-L-lyxo-hexopyranosyl)-11-hydroxy-5-methyl-2-(2-methyl-3-(1-propenyl)oxir anyl)-8-(2,3,6-trideoxy-3-(dimethylamino)-beta-D- arabino-hexopyranosyl)-4H-anthra(1,2-b)pyran- 4,7,12-trione 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Aminoglycosides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Hydroxylamine-Mediated Anthrapyranone Formation, Solving 5-exo/6-endo Issue toward Synthesis of Pluramycin-Class Antibiotics.
In our synthetic study on pluramycin-class antibiotics, an unexpected issue arose, i.e., unfavorable regioselectivity of 5-exo… 
2018
2018
Stereodivergent approach in the protected glycal synthesis of L-vancosamine, L-saccharosamine, L-daunosamine and L-ristosamine involving a ring-closing metathesis step
In this paper, a new access to several chiral 3-aminoglycals as potential precursors for glycosylated natural products is… 
2011
2011
Studies Toward the Syntheses of Pluramycin Natural Products. The First Total Synthesis of Isokidamycin.
2004
2004
DNA damage responses triggered by a highly cytotoxic monofunctional DNA alkylator, hedamycin, a pluramycin antitumor antibiotic.
Long-term exposure (72 h) to hedamycin, a monofunctional DNA alkylator of the pluramycin class of antitumor antibiotics… 
1996
1996
Structural distortions induced by integration host factor (IHF) at the H' site of phage lambda probed by (+)-CC-1065, pluramycin, and KMnO4 and by DNA cyclization studies.
Integration Host Factor (IHF) is a sequence-specific DNA-bending protein that is proposed to interact with DNA primarily through… 
1995
1995
Hedamycin intercalates the DNA helix and, through carbohydrate-mediated recognition in the minor groove, directs N7-alkylation of guanine in the major groove in a sequence-specific manner.
Highly Cited
1993
Highly Cited
1993
Structure of the altromycin B (N7-guanine)-DNA adduct. A proposed prototypic DNA adduct structure for the pluramycin antitumor antibiotics.
Altromycin B belongs to the pluramycin family of antitumor antibiotics, which also includes kidamycin, hedamycin, pluramycin… 
Review
1986
Review
1986
The antibiotics of the pluramycin group (4H-anthra[1,2-b]pyran antibiotics).
The pluramycin-like antibiotics are a group of highly substituted 4H-anthra[1,2-b]pyran-4,7,12-triones. They show antitumor and… 
1985
1985
Largomycin FII chromophore component 4, a new pluramycin antibiotic.
The chromophore of the antitumor chromoprotein largomycin FII is a mixture of components belonging to the pluramycin class of… 
1969
1969
Effects of several tumor-inhibitory antibiotics on immunological responses.
The effects of various tumor-inhibitory antibiotics on immunological responses were investigated, using serum antibody production… 
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