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pimonidazole

Known as: 2-((nitroimidazol-1-yl)methyl)-1-piperdineethanol, 1-piperidineethanol, alpha-((2-nitro-1h-imidazol-1-yl)methyl)-, 2-pimonidazole 
A 2-nitroimidazole with hypoxic selectivity and potential radiosensitizing activities. Pimonidazole is reduced in hypoxic environments such as those… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

NitroimidazolesRadiation-Sensitizing Agents
Pimonidazole Hydrochloride

Narrower (2)

Ro 03-8799hypoxyprobe-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Exploratory study of the prognostic value of microenvironmental parameters during fractionated irradiation in human squamous cell carcinoma xenografts.
2011
2011
Differentiation between hypoxic and non-hypoxic experimental tumors by dynamic contrast-enhanced magnetic resonance imaging.
2010
2010
Preliminary study on the effect of trauma-induced secondary cellular hypoxia in brain injury
2010
2010
Hypoxia and the expression of HIF-1alpha and HIF-2alpha in the retina of streptozotocin-injected mice and rats.
Highly Cited
2009
Highly Cited
2009
Pimonidazole adduct immunohistochemistry in the rat kidney: detection of tissue hypoxia.
Immunohistochemistry for pimonidazole adducts serves to define hypoxia within tissues. For this purpose, pimonidazole is… 
Highly Cited
2006
Highly Cited
2006
Comparison between pimonidazole binding, oxygen electrode measurements, and expression of endogenous hypoxia markers in cancer of the uterine cervix
Although tumor hypoxia has been associated with a more aggressive phenotype and lower cure rate, there is no consensus as to the… 
2006
2006
Adventitial microvessel formation after coronary stenting and the effects of SU11218, a tyrosine kinase inhibitor.
2004
2004
Effects of nicotinamide and carbogen in different murine colon carcinomas: immunohistochemical analysis of vascular architecture and microenvironmental parameters.
Highly Cited
2003
Highly Cited
2003
Pimonidazole binding in C6 rat brain glioma: relation with lipid droplet detection
In C6 rat brain glioma, we have investigated the relation between hypoxia and the presence of lipid droplets in the cytoplasm of… 
1989
1989
Radiosensitizer-DNA interactions in relation to intracellular uptake.
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