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pimagedine

Known as: aminoguanidine, hydrazinecarboximidamide, monoaminoguanidine 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Modern diets are largely heat-processed and as a result contain high levels of advanced glycation end products (AGEs). Dietary… Expand
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Review
2006
Review
2006
Carbonylation of proteins is an irreversible oxidative damage, often leading to a loss of protein function, which is considered a… Expand
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Highly Cited
2005
Highly Cited
2005
Hepcidin is a peptide that regulates iron homeostasis by inhibiting iron absorption by the small intestine and release of iron… Expand
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Review
2003
Review
2003
Aminoguanidine (AG) is a prototype therapeutic agent for the prevention of formation of advanced glycation endproducts. It reacts… Expand
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Highly Cited
2001
Highly Cited
2001
Glia undergo inflammatory activation in most CNS pathologies and are capable of killing cocultured neurons. We investigated the… Expand
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Highly Cited
1997
Highly Cited
1997
Endogenous advanced glycation endproducts (AGEs) include chemically crosslinking species (glycotoxins) that contribute to the… Expand
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Highly Cited
1997
Highly Cited
1997
N(epsilon)-(Carboxymethyl)lysine (CML), a major product of oxidative modification of glycated proteins, has been suggested to… Expand
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Highly Cited
1996
Highly Cited
1996
1 The role of nitric oxide (NO) derived from constitutive and inducible nitric oxide synthase (cNOS and iNOS) and its… Expand
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Highly Cited
1993
Highly Cited
1993
We have evaluated the role of nitric oxide (NO) on the activity of the constitutive and induced forms of cyclooxygenase (COX; COX… Expand
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Highly Cited
1991
Highly Cited
1991
Nitric oxide (an endothelium-derived relaxing factor) induces smooth muscle relaxation and is an important mediator in the… Expand
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