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pimagedine

Known as: aminoguanidine, hydrazinecarboximidamide, monoaminoguanidine 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Enzyme InhibitorsGuanidines
PIMAGEDINE HYDROCHLORIDEguanylhydrazine

Narrower (1)

aminoguanidine sulfate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Regulation of hepcidin transcription by interleukin-1 and interleukin-6.
Hepcidin is a peptide that regulates iron homeostasis by inhibiting iron absorption by the small intestine and release of iron… 
Highly Cited
2003
Highly Cited
2003
Novel inhibitors of advanced glycation endproducts.
Highly Cited
2002
Highly Cited
2002
Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat.
BACKGROUND Nonenzymatic reactions between sugars or lipids and protein and formation of advanced glycation and lipoxidation end… 
Highly Cited
1999
Highly Cited
1999
Interferon‐gamma (IFN‐γ)‐ and tumour necrosis factor (TNF)‐induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)‐induced colitis in mice
Excess nitric oxide formation caused by the activity of the inducible nitric oxide synthase has been implicated as a toxic… 
Highly Cited
1997
Highly Cited
1997
Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells.
Prolonged poor glycemic control in non-insulin-dependent diabetes mellitus patients often leads to a decline in insulin secretion… 
Highly Cited
1994
Highly Cited
1994
Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase.
Enhanced formation of nitric oxide (NO) by both the constitutive and the inducible isoforms of NO synthase (NOS) has been… 
Highly Cited
1994
Highly Cited
1994
The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat
Highly Cited
1992
Highly Cited
1992
Exogenous advanced glycosylation end products induce complex vascular dysfunction in normal animals: a model for diabetic and aging complications.
Advanced glycosylation end products (AGEs) have been implicated in many of the complications of diabetes and normal aging… 
Highly Cited
1991
Highly Cited
1991
Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo.
Highly Cited
1991
Highly Cited
1991
Retardation by Aminoguanidine of Development of Albuminuria, Mesangial Expansion, and Tissue Fluorescence in Streptozocin-Induced Diabetic Rat
This study evaluated the relationship between the development of fluorescence related to advanced glycosylation end products… 
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