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pilsicainide

Known as: tetrahydro-1H-pyrrolizine-7a(5H)-aceto-2',6'-xylidide 
 
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
A novel 3,4,4a-trihydroxanthene-fused pyrrole 2 was synthesized by the reaction of 2,3,4,4a-tetrahydro-1H-xanthen-1-one with 3… Expand
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Highly Cited
2010
Highly Cited
2010
A series of 1-aryl-4-methyl-3,6-bis-(5-methylisoxazol-3-yl)-2-thioxo-2,3,6,10b-tetrahydro-1H-pyrimido[5,4-c]quinolin-5-ones (6a-h… Expand
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2010
2010
Peripheral branches of the trigeminal nerve may be damaged during maxillofacial injury or surgical procedures and trigeminal… Expand
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Highly Cited
2008
Highly Cited
2008
The cyclizations of enynes substituted at the alkyne gives products of formal [4+2] cyclization with Au(I) catalysts. 1,8-Dien-3… Expand
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Highly Cited
2006
Highly Cited
2006
Introduction: Autonomic modulation, particularly high vagal tone, plays an important role in the occurrence of ventricular… Expand
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Highly Cited
2005
Highly Cited
2005
New Au(I) complexes with bulky, biphenyl phosphines are the most reactive catalysts for the cyclizations of enynes. 1,6-Enynes… Expand
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Highly Cited
2004
Highly Cited
2004
Agonist-induced internalization of G protein-coupled receptors (GPCRs) is a well characterized phenomenon believed to contribute… Expand
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Highly Cited
2001
Highly Cited
2001
As a first step in structure-based design of highly selective and potent Cdk4 inhibitors, we performed structure-based generation… Expand
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1998
1998
The present study investigates the possibility that imidazoline receptors mediate modulation of cholinergic motor functions of… Expand
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Highly Cited
1996
Highly Cited
1996
The efficacy and safety of a single oral dose of 150-mg pilsicainide, a new class Ic antiarrhythmic drug, in converting recent… Expand
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