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Inhibition of 5 alpha-reductase and aromatase by the ellagitannins oenothein A and oenothein B from Epilobium species.
- B. Ducrey, A. Marston, S. Göhring, R. Hartmann, K. Hostettmann
- BiologyPlanta medica
- 1 April 1997
TLDR
Allosteric activation of the protein kinase PDK1 with low molecular weight compounds
TLDR
17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: Protein structures, functions, and recent progress in inhibitor development
- S. Marchais-Oberwinkler, C. Henn, J. Adamski
- BiologyThe Journal of Steroid Biochemistry and Molecular…
- 1 May 2011
Antibiotic-free nanotherapeutics: ultra-small, mucus-penetrating solid lipid nanoparticles enhance the pulmonary delivery and anti-virulence efficacy of novel quorum sensing inhibitors.
- N. Nafee, A. Husari, Marc Schneider
- BiologyJournal of controlled release : official journal…
- 28 October 2014
A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase.
- M. Recanatini, A. Bisi, R. Hartmann
- Chemistry, BiologyJournal of medicinal chemistry
- 24 January 2001
TLDR
Discovery of antagonists of PqsR, a key player in 2-alkyl-4-quinolone-dependent quorum sensing in Pseudomonas aeruginosa.
- Cenbin Lu, B. Kirsch, R. Hartmann
- BiologyChemistry & biology
- 23 March 2012
The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis[S]
- S. Laggai, S. Kessler, A. Kiemer
- Biology, MedicineJournal of Lipid Research
- 1 June 2014
TLDR
Rule–based regulatory and metabolic model for Quorum sensing in P. aeruginosa
- N. S. Schaadt, A. Steinbach, R. Hartmann, V. Helms
- BiologyBMC Systems Biology
- 21 August 2013
TLDR
Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections.
TLDR
Effects of novel 17α-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo
- S. Haidar, P. B. Ehmer, S. Barassin, C. Batzl-Hartmann, R. Hartmann
- Biology, ChemistryThe Journal of Steroid Biochemistry and Molecular…
- 1 April 2003
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