phosphoribosylamine
National Institutes of Health
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The YjgF/YER057c/UK114 family of proteins is highly conserved across all three domains of life and currently lacks a consensus…
ABSTRACT Purine nucleotides are essential precursors for living organisms because they are involved in many important processes…
Glycinamide ribonucleotide synthetase (GAR-syn) catalyzes the second step of the de novo purine biosynthetic pathway; the…
Phosphoribosylamine (PRA) is a product of glutamine phosphoribosylpyrophosphate amidotransferase (PRPP-AT) and a substrate for…
Incubation of [1-13C]-5-phosphoribosyl pyrophosphate ([1-13C]PRPP) and glutamine with PRPP amidotransferase results in rapid…
Exogenous purines are known to suppress purine synthesis de novo in bacteria (2-4), HeLa and L cells (5), and ascites cells (6…